Haemophilus influenzae strain 39P18H1 N39P18H1_9_1

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae strain 39P18H1 N39P18H1_9_1 is a Gram-negative, rod-shaped bacterium that is primarily host-associated, specifically linked to Homo sapiens. It is classified as an aerobe and facultative anaerobe, allowing it to thrive in varying oxygen conditions. This strain is mesophilic, with an optimal growth temperature of 35°C, and possesses a unique feature of having two membranes, indicative of its Gram-negative classification. The strain exhibits no mobility, and while it has flagella, it does not utilize them for movement. H. influenzae strain 39P18H1 N39P18H1_9_1 has a single replicon, which contributes to its genetic stability and replication within host environments. This bacterium is known to be free-living but has significant health implications for its human hosts. It is associated with a range of serious health effects, including bacteremia, pneumonia, meningitis, and various forms of respiratory infections. Additionally, it can cause conditions such as necrotizing fasciitis, sepsis, and exacerbations of chronic pulmonary diseases, highlighting its role in both invasive and noninvasive mucosal inflammatory diseases. The ecological insight derived from this information indicates that H. influenzae strain 39P18H1 N39P18H1_9_1 is well-adapted to human hosts and plays a critical role in respiratory health. Understanding its pathogenic potential can inform clinical approaches to diagnosing and treating infections linked to this bacterium, particularly in vulnerable populations such as those with chronic respiratory conditions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
Strainstrain 39P18H1 N39P18H1_9_1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae strain 39P18H1 N39P18H1_9_1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus influenzae strain 39P18H1 N39P18H1_9_1, whole genome

Gene Summary

Adenine Count

579518 bp

Thymine Count

580810 bp

Guanine Count

354619 bp

Cytosine Count

353731 bp

Genome Length

1868678 bp

Protein-coding Genes

1664 genes

Non-Coding Genes

123 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nickel/cobalt efflux protein rcnaBV055_01264Not AvailablePositive1327342 - 132831035748.6
Trna-asnNot AvailableNot AvailablePositive1328413 - 1328488Not Available
uvrabc system protein bBV055_01266Not AvailablePositive1328924 - 133096377562.4
lipoteichoic acid synthase 1BV055_01267Not AvailableNegative1330994 - 133291972157.0
nadp-dependent malic enzymeBV055_01268Not AvailableNegative1333198 - 133546882029.3
hypothetical proteinBV055_01269Not AvailablePositive1335665 - 133628524602.5
ribosomal small subunit pseudouridine synthase aBV055_01270Not AvailablePositive1336375 - 133707326101.9
bicyclomycin resistance proteinBV055_01271Not AvailablePositive1337075 - 133827143449.6
hypothetical proteinBV055_01272Not AvailableNegative1338303 - 133910329521.7
hypothetical proteinBV055_01273Not AvailablePositive1339201 - 133986324201.3

Displaying genes 1301 – 1310 of 1787 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

323 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da

Displaying 1–10 of 323 metabolites

Health Effects

Health ConditionRelationReference
Ear infection (otitis media)CausesPMC10964412
Lung infection (pneumonia)CausesPMC10964412
Exacerbations of chronic pulmonary diseases (e.g., chronic obstructive pulmonary disease, protracted bacterial bronchitis, and bronchiectasis)CausesPMC10964412
Ear infectionCausesPMC10964412
Otitis mediaCausesPMC10964412
Lung infectionCausesPMC10964412
PneumoniaCausesPMC10964412
Invasive diseaseCausesPMC10964412
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026

Displaying health effects 1 – 10 of 60 in total