Streptococcus mitis strain RH_50275_09 s_mitis_RH_50275_09_ID_1

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain RH_50275_09 (s_mitis_RH_50275_09_ID_1) is a Gram-positive cocci bacterium characterized by its arrangement in chains or pairs. It is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is categorized as mesophilic, indicating an optimal growth temperature range suitable for human hosts, specifically Homo sapiens. S. mitis RH_50275_09 is non-motile and does not possess flagella, which suggests a reliance on other means for colonization and dissemination within the host environment. It has a single replicon and a single membrane, which are typical features of many bacterial species, indicating a simpler genomic structure conducive to its adaptability. Ecologically, S. mitis is primarily associated with humans and has been noted for its role in various health conditions, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. These associations underline the pathogenic potential of this strain, despite being a member of the normal flora in the oral cavity and other mucosal surfaces. The presence of S. mitis in human hosts and its potential to cause serious infections indicates its dual role as a free-living organism within the microbiome and as an opportunistic pathogen. Understanding its traits and behaviors is crucial for elucidating its impact on human health, particularly in immunocompromised individuals.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain RH_50275_09 s_mitis_RH_50275_09_ID_1

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain RH_50275_09 s_mitis_RH_50275_09_ID_1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain RH_50275_09 s_mitis_RH_50275_09_ID_1,

Gene Summary

Adenine Count

615739 bp

Thymine Count

621578 bp

Guanine Count

397570 bp

Cytosine Count

422143 bp

Genome Length

2057130 bp

Protein-coding Genes

1961 genes

Non-Coding Genes

117 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcriptional regulatorB7700_03800Not AvailableNegative732910 - 73340719002.2
sorbitol-6-phosphate 2-dehydrogenaseB7700_03810Not AvailableNegative735291 - 73609128460.0
glucose-6-phosphate isomeraseB7700_03815Not AvailableNegative736275 - 73762449445.5
gamma-glutamyl hydrolaseB7700_03820Not AvailableNegative737794 - 73848325492.4
multidrug abc transporter permeaseB7700_03825Not AvailableNegative738622 - 74038865591.0
multidrug abc transporter atp-binding proteinB7700_03830Not AvailableNegative740390 - 74209662758.2
dna mismatch repair protein mutsB7700_03835Not AvailableNegative742242 - 74477694628.5
arginine repressorB7700_03840Not AvailableNegative744827 - 74527317051.8
arginine--trna ligaseB7700_03845Not AvailablePositive745409 - 74710063306.2
marr family transcriptional regulatorB7700_03850Not AvailablePositive747559 - 7478049742.92

Displaying genes 731 – 740 of 2078 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total