Streptococcus mitis strain RH_50275_09 s_mitis_RH_50275_09_ID_1

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain RH_50275_09 (s_mitis_RH_50275_09_ID_1) is a Gram-positive cocci bacterium characterized by its arrangement in chains or pairs. It is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is categorized as mesophilic, indicating an optimal growth temperature range suitable for human hosts, specifically Homo sapiens. S. mitis RH_50275_09 is non-motile and does not possess flagella, which suggests a reliance on other means for colonization and dissemination within the host environment. It has a single replicon and a single membrane, which are typical features of many bacterial species, indicating a simpler genomic structure conducive to its adaptability. Ecologically, S. mitis is primarily associated with humans and has been noted for its role in various health conditions, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. These associations underline the pathogenic potential of this strain, despite being a member of the normal flora in the oral cavity and other mucosal surfaces. The presence of S. mitis in human hosts and its potential to cause serious infections indicates its dual role as a free-living organism within the microbiome and as an opportunistic pathogen. Understanding its traits and behaviors is crucial for elucidating its impact on human health, particularly in immunocompromised individuals.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain RH_50275_09 s_mitis_RH_50275_09_ID_1

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain RH_50275_09 s_mitis_RH_50275_09_ID_1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain RH_50275_09 s_mitis_RH_50275_09_ID_1,

Gene Summary

Adenine Count

615739 bp

Thymine Count

621578 bp

Guanine Count

397570 bp

Cytosine Count

422143 bp

Genome Length

2057130 bp

Protein-coding Genes

1961 genes

Non-Coding Genes

117 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinB7700_00960Not AvailablePositive165775 - 16642824864.4
hypothetical proteinB7700_00965Not AvailablePositive166440 - 16764847148.4
macrolide abc transporter atp-binding proteinB7700_00970Not AvailablePositive167629 - 16831225256.8
permeaseB7700_00975Not AvailablePositive168602 - 16958235815.6
type i glyceraldehyde-3-phosphate dehydrogenaseB7700_00980Not AvailablePositive169759 - 17076935918.8
rna pseudouridine synthaseB7700_00985Not AvailableNegative170838 - 17171334054.3
penicillin-binding proteinB7700_00990Not AvailablePositive171800 - 17399580704.7
50s ribosomal protein l33B7700_00995Not AvailablePositive174048 - 1742005598.88
preprotein translocase subunit seceB7700_01000Not AvailablePositive174210 - 1743867140.9
transcription termination/antitermination protein nusgB7700_01005Not AvailablePositive174440 - 17497620300.2

Displaying genes 251 – 260 of 2078 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total