Streptococcus oralis subsp. oralis strain RH_5486_10

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis subsp. oralis strain RH_5486_10 is a Gram-positive bacterium characterized by its cocci shape and its arrangement in pairs and chains. This strain is a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments, and it is classified as mesophilic, meaning it prefers moderate temperature conditions. Notably, it lacks mobility despite the presence of flagella. This strain is host-associated, primarily found in humans (Homo sapiens), and exhibits a free-living biotic relationship. It is significant in clinical settings due to its potential health impacts, being implicated in serious conditions such as endocarditis, peritonitis, meningitis, and invasive disease, particularly infective endocarditis. The genomic information of this strain is accessible under the accession number NCUU00000000.1, highlighting its relevance for further research and understanding of its pathogenic mechanisms. The presence of this bacterium in human hosts underscores its potential role as a pathogenic organism, which can cause severe health complications. In an ecological context, the ability of S. oralis subsp. oralis strain RH_5486_10 to inhabit the human microbiome while also having the potential to cause invasive diseases illustrates the delicate balance in host-microbe interactions. This highlights the importance of monitoring such microorganisms, as they can transition from benign commensals to opportunistic pathogens under certain conditions.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainsubsp. oralis strain RH_5486_10

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis subsp. oralis strain RH_5486_10
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Ovis aries
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis subsp. oralis strain RH_5486_10

Gene Summary

Adenine Count

589988 bp

Thymine Count

596409 bp

Guanine Count

415993 bp

Cytosine Count

410589 bp

Genome Length

2013163 bp

Protein-coding Genes

1911 genes

Non-Coding Genes

54 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cida/lrga family proteinB7711_02195Not AvailableNegative413332 - 41370614036.1
marr family transcriptional regulatorB7711_02200Not AvailablePositive413903 - 41428314573.5
duf4649 domain-containing proteinB7711_02205Not AvailablePositive414383 - 4146048653.97
thiol reductase thioredoxinB7711_02210Not AvailablePositive414619 - 41493311405.9
7-cyano-7-deazaguanine synthase quecB7711_02215Not AvailablePositive415134 - 41578724297.8
6-carboxytetrahydropterin synthase quedB7711_02220Not AvailablePositive415787 - 41623017595.7
7-carboxy-7-deazaguanine synthase queeB7711_02225Not AvailablePositive416223 - 41693926741.8
nadph-dependent 7-cyano-7-deazaguanine reductase quefB7711_02230Not AvailablePositive416958 - 41744919219.6
aquaporinB7711_02235Not AvailableNegative417507 - 41817522403.1
hypothetical proteinB7711_02240Not AvailablePositive418473 - 41945336932.2

Displaying genes 411 – 420 of 1965 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total