Mycobacterium intracellulare ATCC 13950

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium intracellulare ATCC 13950 is a non-motile bacterium, as indicated by the presence of flagella. It possesses a single replicon, which is characteristic of its genomic structure. The strain is cataloged under the accession number NC_016946.1, providing a reference for its genetic data and sequence information. M. intracellulare is known for its role in human disease, particularly as an opportunistic pathogen. It is part of the Mycobacterium avium complex, which is associated with infections in immunocompromised individuals, such as those with HIV/AIDS. This association highlights the clinical significance of understanding the genetic and physiological traits of this organism. The presence of a single replicon suggests a streamlined genome that may be adapted for survival in specific environments, such as within the host. This trait can impact its ability to replicate and respond to environmental pressures, including antimicrobial treatments. Ecologically, M. intracellulare is often found in water sources and soil, which can facilitate its transmission to humans. Understanding its genomic and physiological traits, such as flagella presence and replicon structure, can provide insights into its adaptability and survival mechanisms in various environments. This knowledge is crucial for developing effective strategies to prevent infections and manage outbreaks associated with this opportunistic pathogen.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium intracellulare
StrainATCC 13950

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium intracellulare ATCC 13950, complete sequence.

Gene Summary

Adenine Count

858868 bp

Thymine Count

864454 bp

Guanine Count

1841817 bp

Cytosine Count

1837263 bp

Genome Length

5402402 bp

Protein-coding Genes

5028 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rv0518 family gdsl lipaseOCU_RS46850Not AvailableNegative4733938 - 473462424064.6
acyltransferase family proteinOCU_RS46855Not AvailableNegative4734715 - 473595345843.6
stas domain-containing proteinOCU_RS46860Not AvailablePositive4736310 - 473675016074.1
hypothetical proteinOCU_RS46865Not AvailableNegative4736734 - 47369948879.84
duf3093 family proteinOCU_RS46870Not AvailableNegative4736991 - 473752119134.9
porphobilinogen synthaseOCU_RS46875Not AvailableNegative4737577 - 473856634621.0
uroporphyrinogen-iii synthaseOCU_RS46880Not AvailableNegative4738612 - 474026757752.7
hydroxymethylbilane synthaseOCU_RS46885Not AvailableNegative4740291 - 474123832717.1
glutamyl-trna reductaseOCU_RS46890Not AvailableNegative4741252 - 474263148170.7
glutaredoxin family proteinOCU_RS46895Not AvailableNegative4742747 - 47430169825.65

Displaying genes 4441 – 4450 of 5081 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001210alpha,alpha'-trehalose 6,6'-bismycolateC76H142O15Chemical structure of alpha,alpha'-trehalose 6,6'-bismycolateNot available
Average1295.957Da
Monoisotopic1295.034874Da
BASm0001216alpha,alpha'-trehalose 6-mycolateC44H82O13Chemical structure of alpha,alpha'-trehalose 6-mycolateNot available
Average819.127Da
Monoisotopic818.5755427Da
BASm0003763(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateC11H12NO6PChemical structure of (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateNot available
Average285.1898Da
Monoisotopic285.0402236Da
BASm0039655Achromobacter xylosoxidans A8Not availableNot availableNot available

Displaying 1–4 of 4 metabolites

Health Effects

No health effects information available for this bacterium.