Mycobacterium intracellulare ATCC 13950

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium intracellulare ATCC 13950 is a non-motile bacterium, as indicated by the presence of flagella. It possesses a single replicon, which is characteristic of its genomic structure. The strain is cataloged under the accession number NC_016946.1, providing a reference for its genetic data and sequence information. M. intracellulare is known for its role in human disease, particularly as an opportunistic pathogen. It is part of the Mycobacterium avium complex, which is associated with infections in immunocompromised individuals, such as those with HIV/AIDS. This association highlights the clinical significance of understanding the genetic and physiological traits of this organism. The presence of a single replicon suggests a streamlined genome that may be adapted for survival in specific environments, such as within the host. This trait can impact its ability to replicate and respond to environmental pressures, including antimicrobial treatments. Ecologically, M. intracellulare is often found in water sources and soil, which can facilitate its transmission to humans. Understanding its genomic and physiological traits, such as flagella presence and replicon structure, can provide insights into its adaptability and survival mechanisms in various environments. This knowledge is crucial for developing effective strategies to prevent infections and manage outbreaks associated with this opportunistic pathogen.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium intracellulare
StrainATCC 13950

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium intracellulare ATCC 13950, complete sequence.

Gene Summary

Adenine Count

858868 bp

Thymine Count

864454 bp

Guanine Count

1841817 bp

Cytosine Count

1837263 bp

Genome Length

5402402 bp

Protein-coding Genes

5028 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter family substrate-binding proteinOCU_RS32660Not AvailableNegative1596139 - 159781559589.6
dipeptide abc transporter atp-binding proteinOCU_RS32665Not AvailableNegative1597808 - 159964365683.2
abc transporter permeaseOCU_RS32670Not AvailableNegative1599640 - 160051531295.1
abc transporter permeaseOCU_RS32675Not AvailableNegative1600617 - 160159434939.2
beta-class carbonic anhydraseOCU_RS32680Not AvailablePositive1601807 - 160229817921.5
paai family thioesteraseOCU_RS32685Not AvailableNegative1602373 - 160276213643.8
sulfate adenylyltransferase subunit cysdOCU_RS32690Not AvailablePositive1602926 - 160385535116.6
adenylyl-sulfate kinaseOCU_RS32695Not AvailablePositive1603855 - 160569667235.1
rrf2 family transcriptional regulatorOCU_RS32700Not AvailablePositive1605755 - 160624017375.7
voc family proteinOCU_RS32705Not AvailableNegative1606258 - 160664714295.6

Displaying genes 1561 – 1570 of 5081 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001210alpha,alpha'-trehalose 6,6'-bismycolateC76H142O15Chemical structure of alpha,alpha'-trehalose 6,6'-bismycolateNot available
Average1295.957Da
Monoisotopic1295.034874Da
BASm0001216alpha,alpha'-trehalose 6-mycolateC44H82O13Chemical structure of alpha,alpha'-trehalose 6-mycolateNot available
Average819.127Da
Monoisotopic818.5755427Da
BASm0003763(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateC11H12NO6PChemical structure of (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateNot available
Average285.1898Da
Monoisotopic285.0402236Da
BASm0039655Achromobacter xylosoxidans A8Not availableNot availableNot available

Displaying 1–4 of 4 metabolites

Health Effects

No health effects information available for this bacterium.