Helicobacter pylori B38

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori B38 is a Gram-negative, microaerophilic bacterium that belongs to the spirilla shape category and is characterized by its single-cell arrangement. This organism is notable for its pathogenicity, as it is associated with various gastrointestinal diseases, including peptic ulcers and gastric cancer. The bacterium is free-living, indicating that it can survive independently within its host-associated habitat. H. pylori B38 possesses flagella, which are essential for its motility, allowing it to navigate through the viscous environment of the stomach. It is nonsporulating and has a mesophilic temperature range, with an optimal growth temperature of 37°C. The bacterium contains a single replicon and is surrounded by two membranes, a feature consistent with its classification as a Gram-negative organism. The ecological role of H. pylori B38 can be significant, as it is often found in the human stomach, where it can influence the microbiome and affect host health. Its pathogenic nature and specific adaptations for survival in a microaerophilic environment underscore its ability to thrive in a niche that is hostile to many other microbial species. Understanding the traits of H. pylori B38 can provide insights into its interactions with the host and its implications for human health, particularly in relation to gastric diseases. The strain is cataloged under the accession number NC_012973.1, which may facilitate further research into its genetic and functional characteristics.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainB38

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori B38
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Helicobacter pylori B38


Gene Summary

Adenine Count

476459 bp

Thymine Count

482853 bp

Guanine Count

304179 bp

Cytosine Count

313267 bp

Genome Length

1576758 bp

Protein-coding Genes

1488 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcription antitermination factor nusbHELPY_RS00015Not AvailableNegative105 - 52115491.9
6,7-dimethyl-8-ribityllumazine synthaseHELPY_RS00020Not AvailableNegative523 - 99316991.7
3-deoxy-8-phosphooctulonate synthaseHELPY_RS00025Not AvailableNegative1003 - 183330257.5
carbonic anhydraseHELPY_RS00030Not AvailableNegative1820 - 248525697.6
orotidine-5'-phosphate decarboxylaseHELPY_RS00035Not AvailablePositive2605 - 328825340.1
pantoate--beta-alanine ligaseHELPY_RS00040Not AvailablePositive3289 - 411931009.9
Trna-gluNot AvailableNot AvailablePositive4133 - 4208Not Available
Trna-aspNot AvailableNot AvailablePositive4272 - 4348Not Available
Trna-valNot AvailableNot AvailablePositive4389 - 4464Not Available
Trna-gluNot AvailableNot AvailablePositive4505 - 4579Not Available

Displaying genes 1 – 10 of 1533 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm0012554N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanineC37H57N7O20Not availableNot available
Average919.893Da
Monoisotopic919.366934423Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014058Myristic acidC14H28O2Chemical structure of Myristic acid544-63-8
Average228.3709Da
Monoisotopic228.20893014Da
BASm0014182Vaccenic acidC18H34O2Chemical structure of Vaccenic acidNULL
Average282.468Da
Monoisotopic282.255880335Da
BASm0014219Palmitoleic acidC16H30O2Chemical structure of Palmitoleic acidNULL
Average254.4082Da
Monoisotopic254.224580204Da
BASm0014222DiethanolamineC4H11NO2Chemical structure of DiethanolamineNULL
Average105.1356Da
Monoisotopic105.078978601Da

Displaying 1–10 of 88 metabolites

Health Effects

No health effects information available for this bacterium.