Clostridium botulinum Ba4 str. 657

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium botulinum Ba4 str. 657 is a pathogenic, anaerobic, Gram-positive bacterium characterized as a rod-shaped organism. It exhibits mobility due to the presence of flagella and can be found in various habitats. This organism is a chemoorganotroph, utilizing organic compounds as its energy source. C. botulinum Ba4 str. 657 is known for its ability to form spores, a key trait that allows it to survive in hostile environments. The bacterium typically arranges itself in pairs, singles, or chains, and thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. It possesses a single replicon and a single membrane, consistent with its classification within the Clostridia class. C. botulinum Ba4 str. 657 is recognized for its pathogenicity, primarily related to the production of botulinum toxin, which can lead to severe foodborne illness. Its free-living biotic relationship indicates that it can exist independently in various environments, which may include soil, water, and decaying organic matter. The ability of C. botulinum Ba4 str. 657 to sporulate not only aids in its survival but also poses a significant public health risk. Understanding the ecological roles and survival strategies of this bacterium is crucial for developing measures to prevent botulism outbreaks and ensure food safety.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium botulinum
Strainstr. 657

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium botulinum Ba4 str. 657
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles - Chains
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Clostridium botulinum Ba4 str. 657, complete sequence.

Gene Summary

Adenine Count

1413914 bp

Thymine Count

1441343 bp

Guanine Count

554896 bp

Cytosine Count

567641 bp

Genome Length

3977794 bp

Protein-coding Genes

3544 genes

Non-Coding Genes

349 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetyl-coa carboxylase biotin carboxylase subunitCLJ_RS20395Not AvailableNegative3930823 - 393216949968.2
3-hydroxyacyl-acp dehydratase fabzCLJ_RS20400Not AvailableNegative3932201 - 393263515732.5
acetyl-coa carboxylase biotin carboxyl carrier proteinCLJ_RS20405Not AvailableNegative3932655 - 393313118012.8
beta-ketoacyl-acp synthase iiCLJ_RS20410Not AvailableNegative3933135 - 393437344108.9
3-oxoacyl-[acyl-carrier-protein] reductaseCLJ_RS20415Not AvailableNegative3934393 - 393513926297.2
acp s-malonyltransferaseCLJ_RS20420Not AvailableNegative3935157 - 393610134712.6
enoyl-[acyl-carrier-protein] reductase fabkCLJ_RS20425Not AvailableNegative3936122 - 393704832777.0
acyl carrier proteinCLJ_RS20430Not AvailableNegative3937175 - 39373998504.15
beta-ketoacyl-acp synthase iiiCLJ_RS20435Not AvailableNegative3937440 - 393842035737.9
marr family winged helix-turn-helix transcriptional regulatorCLJ_RS20440Not AvailableNegative3938413 - 393888918305.1

Displaying genes 3831 – 3840 of 3893 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

103 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00021577-cyano-7-deazaguanineC7H5N5OChemical structure of 7-cyano-7-deazaguanineNot available
Average175.1475Da
Monoisotopic175.0494098Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da

Displaying 1–10 of 103 metabolites

Health Effects

No health effects information available for this bacterium.