Nautilia profundicola AmH

Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH) is a strictly anaerobic, moderately thermophilic, hydrogen-oxidizing, sulfur-reducing chemoautotroph bacterium isolated from the biomass of an Alvinella pompejana episymbiont community along the East Pacific Rise Axial Caldera. It is the first published Epsilonproteobacterium to be isolated from deep-sea hydrothermal vents. It grows at 30-55 degrees Celsius, pH 6.0-9.0 and 2-5 % (w/v) NaCl. Chemolithoautotrophic growth occurs with molecular hydrogen or formate as the electron donor and elemental sulfur as the electron acceptor, producing hydrogen sulfide. Heterotrophic and mixotrophic growth occurs with formate as a source of carbon. It uses the reductive TCA cycle for carbon fixation. It possesses a variety of characteristics typical of organisms living in deep-sea hydrothermal vents including a diverse suite of hydrogenases coupled to a relatively simple electron transport chain, numerous stress response systems, a novel predicted nitrate assimilation pathway with hydroxylamine as a key intermediate, and a gene (rgy) encoding the hallmark protein for hyperthermophilic growth, reverse gyrase. It is a model organism of the anaerobic autotrophic Epsilonproteobacteria at hydrothermal vents. (adapted from PMID: 19197347). (EBI Integr8)