Porphyromonas gingivalis ATCC 33277

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Porphyromonadaceae

Genus

Porphyromonas

Description

Porphyromonas gingivalis ATCC 33277 is a Gram-negative, non-motile, rod-shaped anaerobic bacterium that is primarily associated with host environments. It is classified as a mesophilic organism, with an optimal growth temperature of 37°C, which aligns with the typical human body temperature, suggesting its adaptation to the human oral cavity as a habitat. This bacterium is known for its pathogenicity, playing a significant role in the development of periodontal disease. It is free-living; however, its interaction with the host can lead to detrimental health effects, particularly in the context of oral health. P. gingivalis does not form spores, which is a characteristic of its reproductive strategy and survival mechanism in the host environment. Additionally, P. gingivalis possesses two membranes, indicative of its Gram-negative classification, and has one replicon, which is common among many bacteria. Its lack of mobility and presence of flagella suggest a reliance on environmental factors for movement and colonization rather than active motility. Understanding the traits of P. gingivalis ATCC 33277 helps in elucidating its ecological role in the oral microbiome and its contribution to human disease. Its pathogenic nature and specific environmental adaptations underscore the significance of maintaining oral health to prevent the proliferation of such microorganisms, which can lead to more severe health complications.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyPorphyromonadaceae
GenusPorphyromonas
SpeciesPorphyromonas gingivalis
StrainATCC 33277

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Porphyromonas gingivalis ATCC 33277
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Porphyromonas gingivalis ATCC 33277, complete sequence.

Gene Summary

Adenine Count

609298 bp

Thymine Count

606782 bp

Guanine Count

567867 bp

Cytosine Count

570939 bp

Genome Length

2354886 bp

Protein-coding Genes

2030 genes

Non-Coding Genes

67 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4-hydroxy-tetrahydrodipicolinate reductasePGN_RS09225Not AvailableNegative2169655 - 217037126474.5
deoxyguanosinetriphosphate triphosphohydrolase family proteinPGN_RS09230Not AvailableNegative2170432 - 217177551041.0
yeih family proteinPGN_RS09235Not AvailableNegative2171919 - 217291135568.5
hypothetical proteinPGN_RS09240Not AvailablePositive2173420 - 217377913348.1
tonb-dependent receptorPGN_RS09245Not AvailablePositive2174086 - 217658792721.3
dna repair protein recoPGN_RS09250Not AvailablePositive2177157 - 217789428151.2
phospho-sugar mutasePGN_RS09255Not AvailablePositive2177967 - 217971564853.1
hypothetical proteinPGN_RS12490Not AvailableNegative2179925 - 21800123337.02
is5 family transposasePGN_RS09260Not AvailableNegative2180321 - 218137040313.0
crispr-associated endonuclease cas2PGN_RS09265Not AvailableNegative2189610 - 218987310369.8

Displaying genes 1941 – 1950 of 2097 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

373 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da

Displaying 1–10 of 373 metabolites

Health Effects

No health effects information available for this bacterium.