Vibrio cholerae O395

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Vibrionales

Family

Vibrionaceae

Genus

Vibrio

Description

Vibrio cholerae O395 is a Gram-negative, rod-shaped bacterium known for its pathogenicity, particularly in causing cholera. This organism is heterotrophic, obtaining its energy from organic compounds, and it exhibits a facultative anaerobic metabolism, allowing it to thrive in varying oxygen conditions. V. cholerae O395 is characterized by its single-cell arrangement and the presence of flagella, enabling motility. However, it is noted that the bacterium does not exhibit active mobility. The optimal growth temperature for V. cholerae O395 is around 20°C, and it falls within the mesophilic temperature range, indicating that it thrives in moderate temperature conditions. It has a unique cellular structure with two membranes and possesses one replicon, which is typical for many Gram-negative bacteria. In terms of its ecological role, V. cholerae O395 is free-living, indicating that it can exist independently in various environments, which may include aquatic habitats where it can potentially interact with other microorganisms. The pathogenic nature of this bacterium highlights its significance in public health, particularly in areas where water sanitation may be compromised. Understanding the ecological context of V. cholerae O395 is crucial, as its presence in natural water bodies may facilitate transmission routes for cholera, underscoring the importance of monitoring and controlling its populations to prevent outbreaks. The accession number for this strain is NC_009457.1.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderVibrionales
FamilyVibrionaceae
GenusVibrio
SpeciesVibrio cholerae
StrainO395

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Vibrio cholerae O395
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature20
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNonsporulating
Energy sourceHeterotroph
PathogenicityYes

Genome Summary

Vibrio cholerae O395 chromosome 1, complete sequence.

Gene Summary

Adenine Count

785525 bp

Thymine Count

793642 bp

Guanine Count

721693 bp

Cytosine Count

723209 bp

Genome Length

3024069 bp

Protein-coding Genes

2566 genes

Non-Coding Genes

227 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane protein assembly factor bamaVC0395_RS14565Not AvailableNegative1959454 - 196186589935.2
sigma e protease regulator rsepVC0395_RS14570Not AvailableNegative1961914 - 196327248965.7
1-deoxy-d-xylulose-5-phosphate reductoisomeraseVC0395_RS14575Not AvailableNegative1963269 - 196447743687.1
phosphatidate cytidylyltransferaseVC0395_RS14580Not AvailableNegative1964526 - 196536830869.8
polyprenyl diphosphate synthaseVC0395_RS14585Not AvailableNegative1965386 - 196613828312.1
ribosome recycling factorVC0395_RS14590Not AvailableNegative1966230 - 196678720639.0
ump kinaseVC0395_RS14595Not AvailableNegative1966841 - 196757226197.9
translation elongation factor tsVC0395_RS14600Not AvailableNegative1967760 - 196860229849.0
30s ribosomal protein s2VC0395_RS14605Not AvailableNegative1968734 - 196946226810.2
type i methionyl aminopeptidaseVC0395_RS14610Not AvailablePositive1969803 - 197064531315.7

Displaying genes 1801 – 1810 of 2793 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

235 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da

Displaying 1–10 of 235 metabolites

Health Effects

No health effects information available for this bacterium.