Helicobacter acinonychis str. Sheeba

Gram-negativeSpirillaMotileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter acinonychis strain Sheeba is the causative agent of severe gastritis in large felines such as tigers, lions and cheetahs. H. acinonychis arose 200000 years ago via a host jump of H.pylori from early humans. Its genome is made up of one chromosome and one plasmid. It possesses a large number of highly fragmented genes, many encoding outer membrane proteins. These genes could have been destroyed in order to bypass deleterious responses from the feline host immune system. Five genes are present that are involved in sialylation of cell surface carbohydrates and that were probably acquired by horizontal gene transfer. (EBI Integr8)

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter acinonychis
StrainSheeba

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Helicobacter acinonychis str. Sheeba
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Lion
Cell arrangementSingles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter acinonychis str. Sheeba

NC_008230.1NC_008229.1

Gene Summary

Adenine Count

1379 bp

Thymine Count

1017 bp

Guanine Count

636 bp

Cytosine Count

629 bp

Genome Length

3661 bp

Protein-coding Genes

3 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinHAC_RS07595Not Available+234 - 51510864.1
type ii toxin-antitoxin system yafq family toxinHAC_RS07600Not Available+524 - 79310529.1
replication initiation proteinHAC_RS07605Not Available+1854 - 347663728.0
Hypothetical proteinHAC_RS08400Not Available+1396947 - 139725511445.6
AttlNot AvailableNot Available+1397193 - 1397205Not Available
hypothetical proteinHAC_RS09235Not Available+1397242 - 13973644682.84
Integrase/recombinaseHAC_RS06800Not Available+1397361 - 139849743689.3
Hypothetical proteinHAC_RS08640Not Available+1398497 - 13986736847.56
Putative phage replication proteinHAC_RS06810Not Available+1398675 - 139900412872.7
Hypothetical proteinHAC_RS06815Not Available+1399001 - 139994836951.6

Displaying genes 1 – 10 of 1538 in total

Metabolites

1586 records
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Mass search
Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm00016962-heptyl-3-hydroxy-4(1H)-quinoloneC16H21NO2Chemical structure of 2-heptyl-3-hydroxy-4(1H)-quinoloneNot available
Average259.349Da
Monoisotopic259.15722892Da
BASm0001808corynebactinC39H42N6O18Chemical structure of corynebactinNot available
Average882.789Da
Monoisotopic882.2555585Da
BASm00021577-cyano-7-deazaguanineC7H5N5OChemical structure of 7-cyano-7-deazaguanineNot available
Average175.1475Da
Monoisotopic175.0494098Da
BASm0002593(2E)-dodecenoyl-CoAC33H52N7O17P3SChemical structure of (2E)-dodecenoyl-CoA1066-12-2
Average943.789Da
Monoisotopic943.2353235Da

Displaying 1–10 of 1586 metabolites