Streptococcus pyogenes MGAS10270

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes MGAS10270 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. This organism is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, though it is primarily associated with host organisms. MGAS10270 is non-motile and lacks flagella, indicating a reliance on host mobility for dispersal and transmission. This strain is mesophilic, with an optimal growth temperature of 30°C, indicating a preference for moderate temperature environments. It possesses a single replicon and a single membrane, which is typical for many bacterial species. Importantly, S. pyogenes MGAS10270 is known to be pathogenic, contributing to various human diseases. In terms of ecological relationships, it is classified as free-living, suggesting it can exist independently of a host in certain environments, although its pathogenic nature typically directs its interactions towards host organisms. The accession number for this strain is NC_008022.1, which allows for further genomic exploration and study. Understanding the traits of Streptococcus pyogenes MGAS10270 provides insight into its biological capabilities and ecological roles, particularly in relation to its pathogenicity and its adaptive strategies within host-associated environments. This knowledge can inform studies on its transmission, disease mechanisms, and potential management strategies in clinical settings.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
StrainMGAS10270

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes MGAS10270
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementChains - Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Streptococcus pyogenes MGAS10270, complete sequence.

Gene Summary

Adenine Count

594077 bp

Thymine Count

593150 bp

Guanine Count

371915 bp

Cytosine Count

369110 bp

Genome Length

1928252 bp

Protein-coding Genes

1667 genes

Non-Coding Genes

295 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
formate/nitrite transporter family proteinMGAS10270_RS06020Not AvailableNegative1189726 - 119050527742.4
hypothetical proteinMGAS10270_RS06025Not AvailableNegative1190629 - 119117119704.4
transcription repressor nadrMGAS10270_RS06030Not AvailableNegative1191332 - 119185319176.5
phosphoglycerate mutaseMGAS10270_RS06035Not AvailableNegative1191960 - 119265526037.8
dihydroorotate oxidaseMGAS10270_RS06040Not AvailablePositive1192894 - 119382934336.3
heavy metal translocating p-type atpaseMGAS10270_RS06045Not AvailableNegative1194129 - 119599167722.9
hu family dna-binding proteinMGAS10270_RS06050Not AvailableNegative1196335 - 11966109647.57
ypms family proteinMGAS10270_RS06055Not AvailableNegative1196709 - 119729622648.7
sgnh/gdsl hydrolase family proteinMGAS10270_RS06060Not AvailableNegative1197274 - 119811631924.7
degv family proteinMGAS10270_RS06065Not AvailableNegative1198109 - 119894829953.4

Displaying genes 1301 – 1310 of 1962 in total

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0002858all-trans-undecaprenyl phosphateC55H89O4PChemical structure of all-trans-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da

Displaying 1–10 of 92 metabolites

Health Effects

No health effects information available for this bacterium.