Escherichia coli UTI89

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli UTI89 is a Gram-negative, rod-shaped bacterium that serves as a significant uropathogen in urinary tract infections. This strain is characterized by its facultative anaerobic metabolism, allowing it to thrive in both oxygen-rich and low-oxygen environments. It possesses flagella, granting it mobility, which is crucial for its ability to colonize the urinary tract. UTI89 is adapted to a host-associated habitat, indicating its reliance on a living host for survival and growth. It is nonsporulating and has a single replicon, reflecting its simplicity in genetic structure. The bacterium has two membranes, typical of Gram-negative organisms, which contribute to its pathogenicity. Optimal growth occurs at 37°C, aligning with the human body temperature, and it is classified as mesophilic, indicating its preference for moderate temperature ranges. As a free-living organism, E. coli UTI89 can exist independently outside of its host, yet its pathogenicity underscores its role in urinary infections. This duality in lifestyle highlights the ecological adaptability of this strain, capable of thriving in diverse environments while also posing a risk to human health. Understanding the traits of E. coli UTI89 contributes to broader insights into microbial behavior in host-associated habitats and the mechanisms underlying its pathogenic effects. The accession number for this strain is NC_007946.1.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainUTI89

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli UTI89
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Escherichia coli UTI89, complete sequence.

Gene Summary

Adenine Count

1250197 bp

Thymine Count

1252067 bp

Guanine Count

1279155 bp

Cytosine Count

1284322 bp

Genome Length

5065741 bp

Protein-coding Genes

4475 genes

Non-Coding Genes

457 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
spermidine/putrescine abc transporter atp-binding protein potaUTI89_RS06045Not AvailableNegative1229438 - 123057443057.8
peptidase tUTI89_RS06055Not AvailablePositive1230824 - 123205044912.0
[50s ribosomal protein l16]-arginine 3-hydroxylaseUTI89_RS06060Not AvailableNegative1232099 - 123322042567.2
two-component system sensor histidine kinase phoqUTI89_RS06065Not AvailableNegative1233296 - 123475655283.8
two-component system response regulator phopUTI89_RS06070Not AvailableNegative1234756 - 123542725536.7
adenylosuccinate lyaseUTI89_RS06075Not AvailableNegative1235596 - 123696651531.6
high frequency lysogenization protein hfldUTI89_RS06080Not AvailableNegative1236970 - 123761122935.0
trna 2-thiouridine(34) synthase mnmaUTI89_RS06085Not AvailableNegative1237647 - 123875340917.7
iron/manganese abc transporter permease subunit sitdUTI89_RS06445Not AvailableNegative1283247 - 128410430659.9
iron/manganese abc transporter permease subunit sitcUTI89_RS06450Not AvailableNegative1284101 - 128495830833.7

Displaying genes 1511 – 1520 of 4932 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4852 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4852 metabolites

Health Effects

No health effects information available for this bacterium.