Escherichia coli UTI89

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli UTI89 is a Gram-negative, rod-shaped bacterium that serves as a significant uropathogen in urinary tract infections. This strain is characterized by its facultative anaerobic metabolism, allowing it to thrive in both oxygen-rich and low-oxygen environments. It possesses flagella, granting it mobility, which is crucial for its ability to colonize the urinary tract. UTI89 is adapted to a host-associated habitat, indicating its reliance on a living host for survival and growth. It is nonsporulating and has a single replicon, reflecting its simplicity in genetic structure. The bacterium has two membranes, typical of Gram-negative organisms, which contribute to its pathogenicity. Optimal growth occurs at 37°C, aligning with the human body temperature, and it is classified as mesophilic, indicating its preference for moderate temperature ranges. As a free-living organism, E. coli UTI89 can exist independently outside of its host, yet its pathogenicity underscores its role in urinary infections. This duality in lifestyle highlights the ecological adaptability of this strain, capable of thriving in diverse environments while also posing a risk to human health. Understanding the traits of E. coli UTI89 contributes to broader insights into microbial behavior in host-associated habitats and the mechanisms underlying its pathogenic effects. The accession number for this strain is NC_007946.1.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainUTI89

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli UTI89
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Escherichia coli UTI89, complete sequence.

Gene Summary

Adenine Count

1250197 bp

Thymine Count

1252067 bp

Guanine Count

1279155 bp

Cytosine Count

1284322 bp

Genome Length

5065741 bp

Protein-coding Genes

4475 genes

Non-Coding Genes

457 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar hook assembly protein flgdUTI89_RS05790Not AvailablePositive1176822 - 117751723603.4
flagellar hook protein flgeUTI89_RS05795Not AvailablePositive1177542 - 117874741921.3
flagellar basal-body rod protein flgfUTI89_RS05800Not AvailablePositive1178767 - 117952225885.6
flagellar basal-body rod protein flggUTI89_RS05805Not AvailablePositive1179694 - 118047627745.6
flagellar basal body l-ring protein flghUTI89_RS05810Not AvailablePositive1180529 - 118122724616.9
flagellar basal body p-ring protein flgiUTI89_RS05815Not AvailablePositive1181239 - 118233638171.9
flagellar assembly peptidoglycan hydrolase flgjUTI89_RS05820Not AvailablePositive1182336 - 118327734523.2
flagellar hook-associated protein flgkUTI89_RS05825Not AvailablePositive1183343 - 118498658032.2
flagellar hook-associated protein flglUTI89_RS05830Not AvailablePositive1184998 - 118595134255.8
ribonuclease eUTI89_RS05835Not AvailableNegative1186146 - 1189331118183.0

Displaying genes 1461 – 1470 of 4932 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4852 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4852 metabolites

Health Effects

No health effects information available for this bacterium.