Cutibacterium acnes KPA171202

Cutibacterium acnes KPA171202 is a Gram-positive, anaerobic bacterium characterized by its rod shape and non-motility. It is a member of the host-associated microbiota, commonly found on human skin, particularly in sebaceous glands. This organism thrives optimally at 37°C, which is consistent with its adaptation to the human body, and it is classified as mesophilic, indicating it grows best at moderate temperatures. Cutibacterium acnes KPA171202 has a single replicon and a single membrane, and it does not form spores, which is typical for many bacteria that reside in stable environments like the human skin. Despite being a free-living organism, it primarily exists in a symbiotic relationship with its host, contributing to the skin's microbial ecosystem. The presence of flagella indicates a potential for motility, but it is noted that this strain is non-motile. The significance of Cutibacterium acnes in human health is multifaceted; while it can be associated with conditions like acne, it also plays a role in maintaining skin homeostasis by competing with pathogenic bacteria and modulating the immune response. Understanding the traits of Cutibacterium acnes KPA171202 can provide insights into its ecological role in human skin and its potential impacts on dermatological health.