Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130

Gram-negativeSpirillaNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Leptospiria

Order

Leptospirales

Family

Leptospiraceae

Genus

Leptospira

Description

Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 is a pathogenic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. This organism is an aerobic microbe and thrives optimally at a temperature of 28°C, falling within the mesophilic temperature range. It is associated with host environments, indicating its role in infectious diseases. The strain possesses two replicons, which are essential for its genetic stability and replication. Furthermore, Leptospira interrogans str. Fiocruz L1-130 has two membranes, a feature typical of Gram-negative bacteria, which may contribute to its pathogenic mechanisms. The pathogenicity of this strain underscores its relevance in public health, as it is known to be associated with leptospirosis, a significant zoonotic disease. The strain is cataloged under the accession numbers NC_005823.1 and NC_005824.1, which provide a reference for its genomic data in scientific databases. Understanding the specific traits of Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 can offer insights into its ecological niche and role in disease transmission. The bacterium’s association with hosts suggests it may have adaptations that facilitate survival and propagation in specific environments, thereby influencing the epidemiology of leptospirosis.

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassLeptospiria
OrderLeptospirales
FamilyLeptospiraceae
GenusLeptospira
SpeciesLeptospira interrogans
StrainFiocruz L1-130

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature28
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130

Gene Summary

Adenine Count

1389947 bp

Thymine Count

1388105 bp

Guanine Count

747263 bp

Cytosine Count

751870 bp

Genome Length

4277185 bp

Protein-coding Genes

3430 genes

Non-Coding Genes

52 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinLIC_RS03305Not AvailableNegative781584 - 78254636100.0
eal domain-containing proteinLIC_RS03310Not AvailablePositive782703 - 78398049616.8
la_0442/la_0875 n-terminal domain-containing proteinLIC_RS03315Not AvailableNegative784668 - 78562736319.3
hypothetical proteinLIC_RS03320Not AvailableNegative785645 - 78694650085.7
rna polymerase sigma factorLIC_RS03325Not AvailableNegative786949 - 78747320453.4
sigma factor sigx-regulated lipoprotein srpaLIC_RS03330Not AvailableNegative787762 - 78903645507.9
trna dihydrouridine(20/20a) synthase dusaLIC_RS03335Not AvailableNegative790129 - 79117239333.8
lic10647 family lipoproteinLIC_RS03340Not AvailablePositive791334 - 79235038827.0
bifunctional trna (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase mnmd/fad-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase mnmcLIC_RS03345Not AvailablePositive792350 - 79429373616.7
hypothetical proteinLIC_RS03350Not AvailablePositive795248 - 79622537622.4

Displaying genes 661 – 670 of 3772 in total

Metabolites

633 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da

Displaying 1–10 of 633 metabolites

Health Effects

No health effects information available for this bacterium.