Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130

Gram-negativeSpirillaNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Leptospiria

Order

Leptospirales

Family

Leptospiraceae

Genus

Leptospira

Description

Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 is a pathogenic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. This organism is an aerobic microbe and thrives optimally at a temperature of 28°C, falling within the mesophilic temperature range. It is associated with host environments, indicating its role in infectious diseases. The strain possesses two replicons, which are essential for its genetic stability and replication. Furthermore, Leptospira interrogans str. Fiocruz L1-130 has two membranes, a feature typical of Gram-negative bacteria, which may contribute to its pathogenic mechanisms. The pathogenicity of this strain underscores its relevance in public health, as it is known to be associated with leptospirosis, a significant zoonotic disease. The strain is cataloged under the accession numbers NC_005823.1 and NC_005824.1, which provide a reference for its genomic data in scientific databases. Understanding the specific traits of Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 can offer insights into its ecological niche and role in disease transmission. The bacterium’s association with hosts suggests it may have adaptations that facilitate survival and propagation in specific environments, thereby influencing the epidemiology of leptospirosis.

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassLeptospiria
OrderLeptospirales
FamilyLeptospiraceae
GenusLeptospira
SpeciesLeptospira interrogans
StrainFiocruz L1-130

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature28
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130


Gene Summary

Adenine Count

1389947 bp

Thymine Count

1388105 bp

Guanine Count

747263 bp

Cytosine Count

751870 bp

Genome Length

4277185 bp

Protein-coding Genes

3430 genes

Non-Coding Genes

52 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lic10025 family lipoproteinLIC_RS00135Not AvailablePositive32757 - 3395947335.6
urate hydroxylase puudLIC_RS00140Not AvailablePositive34184 - 3488825748.0
c-type cytochromeLIC_RS00145Not AvailablePositive34892 - 3525113184.0
inositol monophosphatase family proteinLIC_RS00150Not AvailableNegative35248 - 3609631426.7
lic_10030 family proteinLIC_RS00155Not AvailableNegative36116 - 3702735404.6
beta-galactosidaseLIC_RS00160Not AvailableNegative37639 - 3961576418.1
hsp33 family molecular chaperone hsloLIC_RS00165Not AvailablePositive39801 - 4065832819.9
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex atpase subunit type 1 tsaeLIC_RS00170Not AvailablePositive40666 - 4123822116.8
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex dimerization subunit type 1 tsabLIC_RS00175Not AvailablePositive41235 - 4191525728.7
ribonuclease r family proteinLIC_RS00180Not AvailablePositive41921 - 4417688053.6

Displaying genes 41 – 50 of 3772 in total

Metabolites

633 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da

Displaying 1–10 of 633 metabolites

Health Effects

No health effects information available for this bacterium.