Streptococcus pyogenes MGAS315

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes MGAS315 is a Gram-positive, cocci-shaped bacterium primarily associated with host environments. It is arranged in chains or pairs and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic conditions. This organism is non-motile, lacking flagella, which is consistent with its lifestyle as a free-living pathogen. S. pyogenes MGAS315 is known for its pathogenicity, contributing to various human diseases, including pharyngitis, scarlet fever, and skin infections. It has a mesophilic temperature range, with an optimal growth temperature of around 30°C. The bacterium contains one replicon and has a single membrane structure. Notably, S. pyogenes MGAS315 does not form spores, which is characteristic of many pathogenic bacteria that rely on direct transmission to host organisms for survival and propagation. Its ability to occupy a host-associated habitat while also being free-living reflects a versatile ecological strategy that enables it to persist in different environments. Overall, the traits of Streptococcus pyogenes MGAS315 highlight its role as a significant human pathogen, capable of adapting to various conditions while maintaining its infectious potential. This adaptability underscores the importance of understanding its biology for effective management and treatment of infections it causes.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
StrainMGAS315

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes MGAS315
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementChains - Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Streptococcus pyogenes MGAS315, complete sequence.

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1537 genes

Non-Coding Genes

448 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
feccd family abc transporter permeaseSPYM3_RS08100Not AvailableNegative1550936 - 155195836164.0
heme abc transporter substrate-binding protein isdeSPYM3_RS10685Not AvailableNegative1551960 - 155284433442.4
hypothetical proteinSPYM3_RS10810Not AvailableNegative1553259 - 155370216157.4
heme-binding protein shrSPYM3_RS08115Not AvailableNegative1553899 - 1557726142793.0
chap domain-containing proteinSPYM3_RS08120Not AvailableNegative1558201 - 155971254461.2
alanine racemaseSPYM3_RS08125Not AvailableNegative1559799 - 156089939893.2
holo-acp synthaseSPYM3_RS08130Not AvailableNegative1560896 - 156125213263.0
preprotein translocase subunit secaSPYM3_RS08135Not AvailableNegative1561368 - 156388794710.1
mannose-6-phosphate isomerase, class iSPYM3_RS08140Not AvailableNegative1564021 - 156497435617.3
fructokinase scrkSPYM3_RS08145Not AvailableNegative1565069 - 156595331163.1

Displaying genes 1661 – 1670 of 1985 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

84 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da

Displaying 1–10 of 84 metabolites

Health Effects

No health effects information available for this bacterium.