Bacteroides fragilis NCTC 9343

Bacteroides fragilis NCTC 9343 is a significant anaerobic, Gram-negative bacterium known for its role in the human microbiome. This species is a chemoorganotroph, deriving energy from organic compounds, and typically exists as single rod-shaped cells. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, indicating its adaptation to a host-associated habitat. Bacteroides fragilis is characterized by having three replicons and a double membrane system, which is typical of Gram-negative bacteria. While it possesses flagella, this strain is non-motile, suggesting that it relies on other mechanisms for dispersal and colonization within its host environment. This bacterium is free-living in the human gut, where it plays a complex role in maintaining health; however, it is also recognized for its pathogenicity, which can lead to opportunistic infections, particularly in immunocompromised individuals. Ecologically, Bacteroides fragilis contributes to the gut microbiota's stability and functionality, aiding in digestion and the synthesis of essential vitamins. Its presence in the intestines is crucial for a balanced microbial community, reflecting the intricate relationships between host and microbiota. Understanding the traits of Bacteroides fragilis NCTC 9343 is essential for comprehending its dual nature as both a beneficial commensal organism and a potential pathogen.