Corynebacterium diphtheriae NCTC 13129

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium diphtheriae NCTC 13129 is a Gram-positive, non-motile rod-shaped bacterium that is an aerobic organism. This strain is known for its pathogenicity and resides in multiple habitats. It exhibits optimal growth at a temperature of 37°C and falls within the mesophilic temperature range. C. diphtheriae NCTC 13129 possesses one replicon and a single membrane, indicating a simplified cellular structure. The presence of flagella is noted, although the organism itself is not mobile. This suggests that while it has the potential for motility structures, it does not utilize them for movement. The pathogenic nature of C. diphtheriae is significant, as this bacterium is responsible for diphtheria, a serious infectious disease. Understanding the traits of this strain can provide insights into its ecological role in various environments, including its interaction with host organisms and its adaptation to different ecological niches. The ability to thrive in multiple habitats while being pathogenic highlights the complex dynamics between microbial life and host interactions. The accession number for this strain is NC_002935.2, which provides a reference for further genomic studies and research into its pathogenic mechanisms and environmental adaptability.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium diphtheriae
StrainNCTC 13129

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium diphtheriae NCTC 13129
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Corynebacterium diphtheriae NCTC 13129, complete sequence.

Gene Summary

Adenine Count

578357 bp

Thymine Count

579393 bp

Guanine Count

665651 bp

Cytosine Count

665234 bp

Genome Length

2488635 bp

Protein-coding Genes

2243 genes

Non-Coding Genes

119 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
site-specific integraseDIP_RS24335Not AvailableNegative306912 - 30737017084.8
hypothetical proteinDIP_RS13070Not AvailableNegative307596 - 3078057771.23
dna-binding proteinDIP_RS13075Not AvailableNegative307990 - 3081997955.41
rhum family proteinDIP_RS13080Not AvailableNegative308208 - 30852512023.2
rhum family proteinDIP_RS24560Not AvailableNegative308449 - 3086949593.5
hypothetical proteinDIP_RS13085Not AvailablePositive308897 - 30942119419.4
hypothetical proteinDIP_RS13090Not AvailablePositive309550 - 3097537015.96
hypothetical proteinDIP_RS23875Not AvailablePositive309799 - 3099335151.03
hypothetical proteinDIP_RS24080Not AvailablePositive309946 - 3101045814.89
fic family proteinDIP_RS13095Not AvailableNegative310129 - 31128643595.2

Displaying genes 351 – 360 of 2362 in total

Metabolites

131 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm0001971heptanedioateC7H10O4Chemical structure of heptanedioateNot available
Average158.154Da
Monoisotopic158.059006Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da

Displaying 1–10 of 131 metabolites

Health Effects

No health effects information available for this bacterium.