Corynebacterium diphtheriae NCTC 13129

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium diphtheriae NCTC 13129 is a Gram-positive, non-motile rod-shaped bacterium that is an aerobic organism. This strain is known for its pathogenicity and resides in multiple habitats. It exhibits optimal growth at a temperature of 37°C and falls within the mesophilic temperature range. C. diphtheriae NCTC 13129 possesses one replicon and a single membrane, indicating a simplified cellular structure. The presence of flagella is noted, although the organism itself is not mobile. This suggests that while it has the potential for motility structures, it does not utilize them for movement. The pathogenic nature of C. diphtheriae is significant, as this bacterium is responsible for diphtheria, a serious infectious disease. Understanding the traits of this strain can provide insights into its ecological role in various environments, including its interaction with host organisms and its adaptation to different ecological niches. The ability to thrive in multiple habitats while being pathogenic highlights the complex dynamics between microbial life and host interactions. The accession number for this strain is NC_002935.2, which provides a reference for further genomic studies and research into its pathogenic mechanisms and environmental adaptability.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium diphtheriae
StrainNCTC 13129

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium diphtheriae NCTC 13129
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Corynebacterium diphtheriae NCTC 13129, complete sequence.

Gene Summary

Adenine Count

578357 bp

Thymine Count

579393 bp

Guanine Count

665651 bp

Cytosine Count

665234 bp

Genome Length

2488635 bp

Protein-coding Genes

2243 genes

Non-Coding Genes

119 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseDIP_RS19305Not AvailablePositive1667803 - 166887337845.4
adenosylcobinamide-gdp ribazoletransferaseDIP_RS19310Not AvailablePositive1668881 - 166970528825.3
branched-chain amino acid aminotransferaseDIP_RS19315Not AvailableNegative1669782 - 167088839921.1
leucyl aminopeptidaseDIP_RS19320Not AvailablePositive1670998 - 167250052374.9
hypothetical proteinDIP_RS19325Not AvailableNegative1672564 - 167295915271.2
2-oxoglutarate dehydrogenase, e2 component, dihydrolipoamide succinyltransferaseDIP_RS19330Not AvailablePositive1673085 - 167503468621.8
lipoyl(octanoyl) transferase lipbDIP_RS19335Not AvailablePositive1675151 - 167590327510.9
lipoyl synthaseDIP_RS19340Not AvailablePositive1675995 - 167704439125.4
duf4191 domain-containing proteinDIP_RS19345Not AvailablePositive1677107 - 167788028408.0
rdd family proteinDIP_RS19350Not AvailableNegative1677927 - 167840016694.6

Displaying genes 1621 – 1630 of 2362 in total

Metabolites

131 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm0001971heptanedioateC7H10O4Chemical structure of heptanedioateNot available
Average158.154Da
Monoisotopic158.059006Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da

Displaying 1–10 of 131 metabolites

Health Effects

No health effects information available for this bacterium.