Escherichia coli strain KCJK1866

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK1866 is a gram-negative, rod-shaped bacterium found primarily in host-associated environments. This strain exhibits a facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. It is capable of movement, facilitated by the presence of flagella, and typically exists in pairs or as single cells. The optimal growth temperature for KCJK1866 is 37°C, classifying it as mesophilic. It has a single replicon and is characterized by two membranes, which is a typical feature of gram-negative bacteria. KCJK1866 is free living but is associated with a wide range of hosts, including Homo sapiens, various livestock species such as Bos taurus and Sus scrofa, and even plants like Solanum lycopersicum and Brassica oleracea var. italica. This strain is known for its pathogenic potential in humans, contributing to a variety of health issues, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS). Its ability to cause both localized infections, such as peritonitis and clinical mastitis, and systemic issues, such as septicemia and meningitis, highlights its significant impact on health. Ecologically, the broad range of hosts indicates that KCJK1866 may play a role in the transmission of pathogens across species, particularly in environments where human and animal interactions are prevalent. Its presence in both human and animal hosts underlines the importance of monitoring and understanding this strain in relation to public health and disease management.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK1866

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK1866
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK1866

Gene Summary

Adenine Count

1420433 bp

Thymine Count

1420193 bp

Guanine Count

1427708 bp

Cytosine Count

1429160 bp

Genome Length

5697494 bp

Protein-coding Genes

5840 genes

Non-Coding Genes

210 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acid stress protein ibagBHS81_19195Not AvailableNegative3600269 - 36005239452.29
phospholipid abc transporter-binding proteinBHS81_19200Not AvailableNegative3600683 - 360097610681.0
phospholipid-binding proteinBHS81_19205Not AvailableNegative3600976 - 360161123964.0
outer membrane lipid asymmetry maintenance protein mladBHS81_19210Not AvailableNegative3601630 - 360218119577.3
phospholipid abc transporter permeaseBHS81_19215Not AvailableNegative3602186 - 360296827865.0
phospholipid abc transporter atp-binding protein mlafBHS81_19220Not AvailableNegative3602976 - 360378529098.6
calcium/sodium antiporterBHS81_19225Not AvailablePositive3603995 - 360497234742.9
arabinose 5-phosphate isomerase kdsdBHS81_19230Not AvailablePositive3604986 - 360597235198.3
3-deoxy-d-manno-octulosonate 8-phosphate phosphatase kdscBHS81_19235Not AvailablePositive3605993 - 360655920016.3
lps export abc transporter periplasmic protein lptcBHS81_19240Not AvailablePositive3606556 - 360713121703.8

Displaying genes 3721 – 3730 of 6050 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total