Haemophilus influenzae strain 84P15H4 N84P15H4_9_1

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae strain 84P15H4 (N84P15H4_9_1) is a Gram-negative, rod-shaped bacterium that exhibits both aerobic and facultatively anaerobic characteristics. It is non-motile and possesses flagella, indicating its capacity for movement in certain environments despite its lack of mobility in the traditional sense. This strain thrives optimally at a temperature of 35°C and falls within the mesophilic temperature range. H. influenzae strain 84P15H4 is notably associated with human hosts (Homo sapiens) and has a significant role in various health conditions. This bacterium is linked to a wide array of diseases, including bacteremia, pneumonia, meningitis, and necrotizing fasciitis, among others. It is also implicated in respiratory infections and exacerbations of chronic pulmonary diseases such as chronic obstructive pulmonary disease (COPD), indicating its pathogenic potential in both invasive and non-invasive mucosal inflammatory diseases. The strain is characterized by a single replicon and a double membrane structure, which is typical of Gram-negative bacteria, contributing to its resilience in various environments. The ecological insight surrounding H. influenzae strain 84P15H4 highlights its role in human health, particularly in respiratory and systemic infections. Understanding the pathogenic mechanisms and environmental adaptations of this strain is crucial for developing effective treatment strategies and public health interventions against the diseases it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
Strainstrain 84P15H4 N84P15H4_9_1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae strain 84P15H4 N84P15H4_9_1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus influenzae strain 84P15H4 N84P15H4_9_1, whole genome

Gene Summary

Adenine Count

607676 bp

Thymine Count

601834 bp

Guanine Count

375236 bp

Cytosine Count

370097 bp

Genome Length

1954843 bp

Protein-coding Genes

1738 genes

Non-Coding Genes

207 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBV163_01037Not AvailablePositive1059814 - 10599063594.64
NingBV163_01038Not AvailablePositive1059906 - 106049322617.5
Putative anti-termination protein qBV163_01039Not AvailablePositive1060495 - 106086013905.2
Gp9, cpp15BV163_01040Not AvailablePositive1061102 - 106192331829.4
hypothetical proteinBV163_01041Not AvailablePositive1062334 - 106284618878.6
Hypothetical proteinBV163_01042Not AvailablePositive1062976 - 10631496422.12
Trna,type:trp,anti_codon:cca;Not AvailableNot AvailablePositive1063212 - 1063285Not Available
HolinBV163_01044Not AvailablePositive1063348 - 10635999597.64
LysozymeBV163_01045Not AvailablePositive1063580 - 106412219835.3
Putative lytic protein rzBV163_01046Not AvailablePositive1064095 - 106443012653.1

Displaying genes 11 – 20 of 1945 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

323 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da

Displaying 1–10 of 323 metabolites

Health Effects

Health ConditionRelationReference
Ear infection (otitis media)CausesPMC10964412
Lung infection (pneumonia)CausesPMC10964412
Exacerbations of chronic pulmonary diseases (e.g., chronic obstructive pulmonary disease, protracted bacterial bronchitis, and bronchiectasis)CausesPMC10964412
Ear infectionCausesPMC10964412
Otitis mediaCausesPMC10964412
Lung infectionCausesPMC10964412
PneumoniaCausesPMC10964412
Invasive diseaseCausesPMC10964412
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026

Displaying health effects 1 – 10 of 60 in total