Escherichia coli strain TH14515 cps locus K1 genomic sequence.

Escherichia coli strain TH14515, with accession number MZ339217.1, is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, thriving optimally at 37°C, and is mesophilic in nature. This strain typically exists in pairs or as single cells, indicating its diverse cellular arrangement. E. coli TH14515 is host-associated, with a broad range of potential hosts including Homo sapiens, Gallus gallus, Bos taurus, various mammals, and even some plants like Solanum lycopersicum and Brassica oleracea var. italica. This extensive host range suggests a significant ecological versatility, allowing this strain to inhabit varied environments and engage in complex interactions with different organisms. The strain is known for its pathogenicity in humans, being linked to a wide array of health effects. These include urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis, hemolytic uremic syndrome (HUS), and septicemia. The presence of TH14515 in clinical settings points to its role as a pathogen capable of causing serious health complications, particularly in vulnerable populations. The strain's ability to infect multiple hosts and its association with various diseases highlights its importance in both human health and veterinary medicine. Understanding the genomic characteristics of E. coli TH14515 can help in devising strategies for controlling infections and managing outbreaks related to this versatile pathogen.