Streptococcus mitis strain CCUG 63687

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain CCUG 63687 is a Gram-positive cocci bacterium that typically arranges itself in chains and pairs. It is a facultative anaerobe, capable of surviving in both oxygen-rich and oxygen-poor environments, and is classified as mesophilic, thriving at moderate temperatures. This strain does not possess mobility due to the absence of flagella and is nonsporulating, indicating it does not form spores. S. mitis strain CCUG 63687 is associated primarily with Homo sapiens, where it exists as a free-living organism within the host. However, it is also known to be implicated in several health conditions, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis, highlighting its potential pathogenicity in humans. With a single replicon and a single membrane structure, this bacterium's genetic and cellular organization supports its adaptability to various environments within the human host. The ability to thrive in different oxygen conditions suggests that it can exploit various niches within the human body, potentially contributing to its role in both commensal and pathogenic contexts. Overall, the ecological insight provided by the characteristics of S. mitis strain CCUG 63687 underscores its dual nature as both a resident of human microbiota and a potential opportunistic pathogen, reflecting the complex relationships that exist between human hosts and microbial inhabitants.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain CCUG 63687

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain CCUG 63687
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain CCUG 63687 63687_ctg_0000009, whole

Gene Summary

Adenine Count

617675 bp

Thymine Count

608191 bp

Guanine Count

404135 bp

Cytosine Count

409084 bp

Genome Length

2039754 bp

Protein-coding Genes

1881 genes

Non-Coding Genes

150 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
zinc-dependent alcohol dehydrogenaseB0686_08275Not AvailableNegative1629207 - 163022635764.1
had family hydrolaseB0686_08285Not AvailableNegative1630604 - 163141630766.8
ncs2 family permeaseB0686_08290Not AvailablePositive1631606 - 163302449283.0
caax protease family proteinB0686_08295Not AvailablePositive1633074 - 163378425993.9
dihydropteroate synthaseB0686_08300Not AvailablePositive1633909 - 163485334414.3
dihydrofolate synthaseB0686_08305Not AvailablePositive1634855 - 163617749250.1
gtp cyclohydrolase i foleB0686_08310Not AvailablePositive1636158 - 163671220759.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinaseB0686_08315Not AvailablePositive1636871 - 163768331109.6
gtp cyclohydrolaseB0686_08320Not AvailableNegative1637728 - 163804512306.5
catabolite control protein aB0686_08325Not AvailablePositive1638281 - 163929137166.2

Displaying genes 1691 – 1700 of 2031 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total