Klebsiella pneumoniae strain MB369

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain MB369 is a Gram-negative, rod-shaped bacterium that exhibits a range of pathogenicity, particularly in humans. It is known to cause various health issues, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. This strain is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, and it is classified as a chemoheterotroph, utilizing organic compounds for energy. The organism typically displays a cell arrangement characterized by chains, pairs, and singles, and it possesses flagella, which contribute to its mobility. The optimal growth temperature for K. pneumoniae MB369 is 37°C, placing it within the mesophilic temperature range. This strain has one replicon and a double membrane structure, consistent with other members of the Enterobacteriaceae family. K. pneumoniae MB369 is notably free-living and has a diverse range of potential hosts, including Homo sapiens, various animals such as Gallus gallus (chickens), Sus scrofa (pigs), and even some plant species (Viridiplantae). This versatility in host associations and its pathogenic capabilities underscore the ecological significance of K. pneumoniae in various environments. Understanding these traits can aid in addressing its impact on human health and managing infections it may cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain MB369

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain MB369
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain MB369


Gene Summary

Adenine Count

1855232 bp

Thymine Count

1847655 bp

Guanine Count

1961618 bp

Cytosine Count

1971925 bp

Genome Length

7636430 bp

Protein-coding Genes

7745 genes

Non-Coding Genes

247 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Dead/deah box helicase family proteinBU230_05950Not AvailablePositive1147642 - 114908154359.0
Portal proteinBU230_05955Not AvailablePositive1149072 - 115062858450.7
Head proteinBU230_05960Not AvailablePositive1150616 - 115153334049.6
Prohead proteaseBU230_05965Not AvailablePositive1151655 - 115286645044.4
Major capsid proteinBU230_05970Not AvailablePositive1152895 - 115382134070.9
Hypothetical proteinBU230_05975Not AvailablePositive1153833 - 115415612398.6
Duf3199 family proteinBU230_05980Not AvailablePositive1154158 - 115453814646.5
Head completion proteinBU230_05985Not AvailablePositive1154541 - 115491814518.8
Tail completion proteinBU230_05990Not AvailablePositive1154918 - 115533115242.0
Tail tube terminatorBU230_05995Not AvailablePositive1155346 - 115570213486.0

Displaying genes 1 – 10 of 7992 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 49 in total