Campylobacter coli strain VA46

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter coli strain VA46 is a Gram-negative bacterium categorized as a microaerophile, meaning it thrives in environments with reduced oxygen levels. This strain is notable for its single replicon, indicating a relatively simple genetic structure. It has been identified as a pathogen affecting various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and Bos (cattle). The health implications of Campylobacter coli strain VA46 are significant, as it is associated with a range of infections and diseases. These include bloodstream infections, urinary tract infections, and intestinal campylobacteriosis, which can lead to enteritis and other diarrheal diseases. This strain contributes to the broader category of enteric diseases, particularly acute bacterial enteritis, which affects the gastrointestinal tract and results in inflammation. The presence of Campylobacter coli in both humans and livestock underscores its ecological importance and potential for zoonotic transmission. This connection highlights the need for monitoring and controlling Campylobacter spp. in agricultural settings to prevent outbreaks and safeguard public health. Understanding the specific traits and behaviors of strains like VA46 can aid in developing strategies to mitigate their impact on human health and enhance food safety practices. The accession number for this strain is MPIX00000000.1, which may serve as a reference for further genomic studies and analysis.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter coli
Strainstrain VA46

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Campylobacter coli strain VA46
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter coli strain VA46 Contig_42, whole genome shotgun

Gene Summary

Adenine Count

674994 bp

Thymine Count

671439 bp

Guanine Count

305511 bp

Cytosine Count

302440 bp

Genome Length

1954479 bp

Protein-coding Genes

1896 genes

Non-Coding Genes

48 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lytic transglycosylaseBOQ02_04005Not AvailableNegative787742 - 78887543164.5
hydrolase tatdBOQ02_04010Not AvailableNegative788878 - 78969031213.5
diguanylate cyclase response regulatorBOQ02_04015Not AvailableNegative789681 - 79092546347.0
dna recombination protein recnBOQ02_04020Not AvailableNegative791014 - 79253758020.7
nad(+) kinaseBOQ02_04025Not AvailableNegative792537 - 79339732171.9
aspartate--trna ligaseBOQ02_04030Not AvailablePositive793490 - 79524166102.6
adenylate kinaseBOQ02_04035Not AvailablePositive795238 - 79581321103.5
inorganic pyrophosphataseBOQ02_04040Not AvailablePositive795823 - 79634119327.4
peptide-methionine (s)-s-oxide reductaseBOQ02_04045Not AvailablePositive796389 - 79688919198.7
hypothetical proteinBOQ02_04050Not AvailableNegative797114 - 79798933383.4

Displaying genes 781 – 790 of 1944 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Intestinal campylobacteriosisCausesPMC10942002
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
EnteritisCausesPMC13255289
Bloodstream infectionsCausesPMC13255289
Urinary tract infectionsCausesPMC13255289
Bacterial enteritisCausesPMC4108124
Acute bacterial enteritisCausesPMC4108124
Enteric diseaseCausesPMC9565744
CampylobacteriosisCausesPMC9565744

Displaying health effects 1 – 10 of 12 in total