Campylobacter coli strain VA46

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter coli strain VA46 is a Gram-negative bacterium categorized as a microaerophile, meaning it thrives in environments with reduced oxygen levels. This strain is notable for its single replicon, indicating a relatively simple genetic structure. It has been identified as a pathogen affecting various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and Bos (cattle). The health implications of Campylobacter coli strain VA46 are significant, as it is associated with a range of infections and diseases. These include bloodstream infections, urinary tract infections, and intestinal campylobacteriosis, which can lead to enteritis and other diarrheal diseases. This strain contributes to the broader category of enteric diseases, particularly acute bacterial enteritis, which affects the gastrointestinal tract and results in inflammation. The presence of Campylobacter coli in both humans and livestock underscores its ecological importance and potential for zoonotic transmission. This connection highlights the need for monitoring and controlling Campylobacter spp. in agricultural settings to prevent outbreaks and safeguard public health. Understanding the specific traits and behaviors of strains like VA46 can aid in developing strategies to mitigate their impact on human health and enhance food safety practices. The accession number for this strain is MPIX00000000.1, which may serve as a reference for further genomic studies and analysis.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter coli
Strainstrain VA46

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Campylobacter coli strain VA46
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter coli strain VA46 Contig_42, whole genome shotgun

Gene Summary

Adenine Count

674994 bp

Thymine Count

671439 bp

Guanine Count

305511 bp

Cytosine Count

302440 bp

Genome Length

1954479 bp

Protein-coding Genes

1896 genes

Non-Coding Genes

48 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellin modification protein aBOQ02_01200Not AvailableNegative244502 - 24527228520.4
flagellar modification protein bBOQ02_01205Not AvailableNegative245272 - 24597926504.8
flagellin modification protein ptmfBOQ02_01210Not AvailableNegative245972 - 24687735571.8
alcohol dehydrogenaseBOQ02_01215Not AvailableNegative246874 - 24790539319.3
udp-n-acetyl-d-glucosamine 2-epimerase, udp-hydrolysingBOQ02_01220Not AvailableNegative247910 - 24906743658.4
n-acetylneuraminate synthaseBOQ02_01225Not AvailableNegative249060 - 25006436904.6
n-acetyl sugar amidotransferaseBOQ02_01235Not AvailableNegative250798 - 25191943731.2
methyl-accepting chemotaxis proteinBOQ02_01240Not AvailableNegative252307 - 25394461062.7
prepilin-type n-terminal cleavage/methylation domain-containing proteinBOQ02_01245Not AvailableNegative254013 - 25478029199.7
hypothetical proteinBOQ02_01250Not AvailableNegative254749 - 25597248009.1

Displaying genes 241 – 250 of 1944 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Intestinal campylobacteriosisCausesPMC10942002
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
EnteritisCausesPMC13255289
Bloodstream infectionsCausesPMC13255289
Urinary tract infectionsCausesPMC13255289
Bacterial enteritisCausesPMC4108124
Acute bacterial enteritisCausesPMC4108124
Enteric diseaseCausesPMC9565744
CampylobacteriosisCausesPMC9565744

Displaying health effects 1 – 10 of 12 in total