Escherichia coli strain 726

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 726 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe, capable of thriving in various oxygen conditions. This strain is motile, possessing flagella, and typically arranges itself in pairs and singles. Its optimal growth temperature is 37°C, placing it within the mesophilic range. E. coli strain 726 is primarily host-associated, with a wide range of potential hosts that includes mammals such as Homo sapiens (humans), Gallus gallus (chickens), and Bos taurus (cattle), among others. This strain can also infect various other vertebrates and some invertebrates, indicating its adaptability and ecological versatility. The health effects associated with E. coli strain 726 are significant, as it is known to cause a variety of serious conditions, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It is implicated in numerous health issues, such as septicemia, diarrhea, and hemolytic uremic syndrome (HUS), highlighting its pathogenic potential. Strain 726’s biotic relationship is classified as free-living, suggesting it can survive independently in various environments. This adaptability may contribute to its role in both environmental and clinical settings, where it can be a source of infection and disease transmission. In conclusion, the widespread host range and diverse pathogenic effects of E. coli strain 726 underscore its ecological and medical significance, emphasizing the need for continued research and surveillance to mitigate its impacts on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 726

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 726
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 726 BN4_726_1_(paired)_contig_1557, whole

Gene Summary

Adenine Count

1610393 bp

Thymine Count

1606516 bp

Guanine Count

1727893 bp

Cytosine Count

1741789 bp

Genome Length

6687406 bp

Protein-coding Genes

5854 genes

Non-Coding Genes

222 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBK400_21960Not AvailableNegative4496826 - 449850266248.6
hypothetical proteinBK400_21965Not AvailableNegative4498597 - 449911219505.6
hypothetical proteinBK400_21970Not AvailableNegative4499159 - 449958416021.5
integraseBK400_21975Not AvailableNegative4499824 - 450094843053.3
molybdopterin-guanine dinucleotide biosynthesis protein bBK400_21985Not AvailableNegative4501708 - 450223519364.5
molybdenum cofactor guanylyltransferase mobaBK400_21990Not AvailableNegative4502217 - 450280121639.1
hypothetical proteinBK400_21995Not AvailablePositive4502871 - 450314010273.5
stress response serine/threonine protein kinase yiheBK400_22000Not AvailablePositive4503217 - 450420338145.5
protein disulfide oxidoreductase dsbaBK400_22005Not AvailablePositive4504220 - 450484623105.8
hypothetical proteinBK400_22010Not AvailablePositive4505001 - 450643152608.8

Displaying genes 4371 – 4380 of 6076 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total