Escherichia coli strain 675

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 675 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is characterized by its ability to move, possessing flagella, and it typically exists in pairs or single arrangements. Its optimal growth temperature is around 37°C, fitting within the mesophilic temperature range. This strain is primarily host-associated, displaying a diverse biotic relationship with numerous hosts, including Homo sapiens, various livestock like Bos taurus and Sus scrofa, and even some plants such as Solanum lycopersicum and Brassica oleracea var. italica. Such a wide range of hosts highlights its ecological versatility and potential for transmission across different species. E. coli strain 675 is known for its pathogenicity in humans, being linked to several severe health effects, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It is also associated with more complex medical conditions such as hemolytic uremic syndrome (HUS) and various forms of sepsis and colitis. The presence of this strain in multiple hosts suggests its role not only as a pathogen but also as a significant contributor to foodborne infections and environmental health concerns. In summary, the ecological insight provided by E. coli strain 675's extensive host range and its pathogenic potential underscores the importance of monitoring this bacterium within both clinical and environmental contexts to mitigate its health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 675

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 675
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 675 BN4_675_1_(paired)_contig_211, whole

Gene Summary

Adenine Count

1412130 bp

Thymine Count

1410724 bp

Guanine Count

1432890 bp

Cytosine Count

1445090 bp

Genome Length

5702057 bp

Protein-coding Genes

5174 genes

Non-Coding Genes

280 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tyrosine-type recombinase/integraseBK375_14585Not AvailableNegative2990845 - 299184038138.1
Repressor protein cBK375_14590Not AvailableNegative2991910 - 299225112546.1
Regulatory proteinBK375_14595Not AvailablePositive2992355 - 299287619575.8
hypothetical proteinBK375_14600Not AvailablePositive2992885 - 29930917504.6
Hypothetical proteinBK375_14605Not AvailablePositive2993374 - 299368211805.7
Duf4754 family proteinBK375_14610Not AvailablePositive2993721 - 29939638551.06
Membrane proteinBK375_14615Not AvailablePositive2993960 - 29940854655.02
hypothetical proteinBK375_14620Not AvailablePositive2994276 - 29944586855.27
hypothetical proteinBK375_14625Not AvailablePositive2994469 - 29946787836.3
Hypothetical proteinBK375_14630Not AvailablePositive2994675 - 29948877914.4

Displaying genes 21 – 30 of 5454 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total