Escherichia coli strain 708

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 708 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. This strain is associated with various hosts, including Homo sapiens, Gallus gallus (chickens), Bos taurus (cattle), and several other vertebrates and invertebrates, indicating its versatility in occupying diverse ecological niches. E. coli 708 typically exists in pairs or singles and possesses flagella, allowing for mobility. It thrives optimally at 37°C and falls within the mesophilic temperature range. This strain is known for its pathogenicity in humans, where it is implicated in a range of health issues including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and septicemia. The bacterium can lead to severe conditions such as hemorrhagic colitis, hemolytic uremic syndrome (HUS), and even contribute to colorectal cancer. These health effects highlight its potential as a serious opportunistic pathogen. In addition to its pathogenic capabilities, E. coli strain 708 exhibits a free-living biotic relationship, suggesting a complex interaction with its environment and hosts. Its ability to infect a wide variety of hosts, including mammals, birds, and even plants, underscores its adaptability and ecological significance. The strain's extensive pathogenic repertoire emphasizes the importance of monitoring its presence in both clinical and environmental contexts to mitigate potential health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 708

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 708
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 708 BN4_708_1_(paired)_contig_191, whole

Gene Summary

Adenine Count

1385987 bp

Thymine Count

1388097 bp

Guanine Count

1418668 bp

Cytosine Count

1420601 bp

Genome Length

5614377 bp

Protein-coding Genes

5173 genes

Non-Coding Genes

339 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
PmgmBK373_14070Not AvailableNegative2806806 - 280738421864.3
Putative morphogenetic protein pmglBK373_14075Not AvailableNegative2807387 - 28076329277.92
Base plate protein gp26BK373_14080Not AvailablePositive2807779 - 280815614457.5
Tail stability protein gp25BK373_14085Not AvailablePositive2808166 - 280938345835.8
Tail proteinBK373_14090Not AvailablePositive2809387 - 281011527147.3
Baseplate protein gp24BK373_14095Not AvailablePositive2810102 - 281088728888.2
Tail length protein gp6BK373_14100Not AvailablePositive2810889 - 281190537226.5
Base plate protein gp5BK373_14105Not AvailablePositive2811898 - 281253021671.6
Hypothetical proteinBK373_14110Not AvailableNegative2812577 - 281357537356.6
Replicative dna helicaseBK373_14115Not AvailableNegative2813575 - 281493950457.1

Displaying genes 71 – 80 of 5512 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total