Escherichia coli strain VL119

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain VL119 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile, possessing flagella, and typically arranges itself in pairs or singles. Its optimal growth temperature is 37°C, categorizing it as mesophilic. E. coli VL119 is primarily host-associated, with a diverse range of hosts that include various mammals, birds, and even plants. Notable hosts encompass Homo sapiens, Gallus gallus, Bos taurus, and several others, indicating its ecological versatility. This strain demonstrates a biotic relationship as a free-living organism, which can inhabit various environments within its host organisms. Importantly, E. coli VL119 is associated with numerous health effects, particularly in humans. It is linked to urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The bacterium can also cause foodborne infections and is implicated in various inflammatory diseases. The wide host range and the significant health impacts of E. coli VL119 highlight its ecological role as both a commensal organism and a potential pathogen. Its presence in diverse environments and hosts suggests a complex interplay within microbial communities, emphasizing the need for ongoing research to understand its pathogenic mechanisms and implications for public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain VL119

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain VL119
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain VL119 contig_0160, whole genome shotgun

Gene Summary

Adenine Count

1336104 bp

Thymine Count

1342140 bp

Guanine Count

1359106 bp

Cytosine Count

1368369 bp

Genome Length

5405719 bp

Protein-coding Genes

4798 genes

Non-Coding Genes

446 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
autoinducer-2 kinaseBHF46_11425Not AvailableNegative2387933 - 238952557586.1
transcriptional regulator lsrrBHF46_11430Not AvailableNegative2389604 - 239055733800.0
autoinducer 2 abc transporter atp-binding protein lsraBHF46_11435Not AvailablePositive2390806 - 239234155846.8
autoinducer 2 abc transporter permease lsrcBHF46_11440Not AvailablePositive2392335 - 239336336435.1
histidine kinaseBHF46_11445Not AvailablePositive2393363 - 239435534490.6
autoinducer 2-binding protein lsrbBHF46_11450Not AvailablePositive2394367 - 239538936603.8
autoinducer 2 aldolaseBHF46_11455Not AvailablePositive2395416 - 239629131866.6
autoinducer-2 (ai-2) modifying protein lsrgBHF46_11460Not AvailablePositive2396315 - 239660511255.4
trans-aconitate 2-methyltransferaseBHF46_11465Not AvailablePositive2396662 - 239742028987.4
hypothetical proteinBHF46_11470Not AvailableNegative2397424 - 239833834811.0

Displaying genes 2561 – 2570 of 5244 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total