Helicobacter pylori strain MG2011-41

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain MG2011-41 is a gram-negative bacterium characterized by its spirilla shape and presence of flagella, which aid in its movement. This strain is microaerophilic, indicating that it requires a low level of oxygen for growth, and it thrives optimally at a temperature of 37°C, placing it within the mesophilic range. H. pylori is predominantly found in host-associated environments, with a notable association with various hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), and several other mammals and avian species. As a free-living organism within its ecological niche, H. pylori strain MG2011-41 has been linked to numerous health conditions, particularly those affecting the gastric system. It is known to cause chronic gastric inflammation, gastric ulcers, and is a significant risk factor for gastric cancer, including adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Other related conditions include functional dyspepsia, atrophic gastritis, and various forms of gastrointestinal disease. The pathogenicity of H. pylori in humans highlights its role as a critical player in gastric health and disease. Its ability to induce an asymptomatic mucosal inflammatory response can lead to chronic conditions that significantly impact human health. Understanding the ecological dynamics of this strain within its various hosts can provide insights into its transmission, pathogenic mechanisms, and potential prevention strategies for associated diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain MG2011-41

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain MG2011-41
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain MG2011-41 MC2011-41_Contig200, whole

Gene Summary

Adenine Count

519162 bp

Thymine Count

521811 bp

Guanine Count

337468 bp

Cytosine Count

339069 bp

Genome Length

1717511 bp

Protein-coding Genes

1497 genes

Non-Coding Genes

44 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
menaquinone biosynthesis proteinBGL70_07965Not AvailablePositive1523133 - 152381626677.8
sortaseBGL70_07970Not AvailableNegative1523781 - 152471033414.5
hypothetical proteinBGL70_07975Not AvailableNegative1524727 - 152498410182.3
fucosyltransferaseBGL70_07980Not AvailablePositive1524985 - 152591636005.0
hypothetical proteinBGL70_07985Not AvailablePositive1525917 - 152808678051.1
hypothetical proteinBGL70_07990Not AvailableNegative1528080 - 15282747637.51
acyl-coa thioesteraseBGL70_08005Not AvailableNegative1529322 - 152984619495.6
short-chain dehydrogenase/reductaseBGL70_08010Not AvailablePositive1529986 - 153084031373.0
iron abc transporter permeaseBGL70_08015Not AvailablePositive1530833 - 153181334626.0
iron abc transporter atp-binding proteinBGL70_08020Not AvailablePositive1531813 - 153258028713.5

Displaying genes 1371 – 1380 of 1541 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total