Escherichia coli strain HE-MDREc68

Escherichia coli strain HE-MDREc68 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is primarily associated with various hosts, including humans (Homo sapiens), domestic animals like chickens (Gallus gallus) and cattle (Bos taurus), as well as numerous other vertebrates and invertebrates. It has been identified in a range of environments, primarily in host-associated habitats, indicating its adaptability and potential for transmission across species. The optimal growth temperature for HE-MDREc68 is 37°C, placing it within the mesophilic temperature range. This strain has a single replicon and possesses a double membrane structure, characteristic of Gram-negative bacteria. HE-MDREc68 is known to be pathogenic to humans, being associated with a variety of health issues including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as septicemia and hemolytic uremic syndrome (HUS). Its pathogenic potential is underscored by its ability to cause diseases ranging from mild diarrhea to severe neonatal meningitis and even colorectal cancer. The wide array of hosts and the serious health effects linked to HE-MDREc68 suggest an ecological versatility that enhances its survival and spread. This adaptability may facilitate its role as both a free-living organism and a pathogenic agent, illustrating the complex interactions between microbial life and host organisms in various environments. Understanding such strains is crucial for developing effective public health strategies and interventions.