Helicobacter pylori strain 2029

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 2029 is a gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella. It is primarily found in host-associated habitats, indicating its dependency on specific hosts for survival and replication. The strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the average human body temperature, facilitating its association with Homo sapiens and other hosts including Gallus gallus (chickens), various Aves, primates, and several mammalian species. This strain has a single replicon and is composed of two membranes, characteristic of its gram-negative classification. Its biotic relationship is categorized as free-living, suggesting it can exist independently within its host environment, yet it is primarily pathogenic in humans. The health effects associated with Helicobacter pylori strain 2029 include a range of gastrointestinal diseases such as chronic gastric inflammation, peptic ulcers, and various forms of gastric cancer, including adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Given its significant role in chronic gastric conditions, the presence of Helicobacter pylori strain 2029 in human populations poses a substantial public health concern. Its association with serious diseases underscores the importance of understanding its pathogenic mechanisms and interactions within the gastrointestinal tract. This insight into its pathogenicity and health impacts can inform strategies for prevention and treatment of related gastrointestinal diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 2029

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 2029
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2029 contig_9, whole genome shotgun

Gene Summary

Adenine Count

504008 bp

Thymine Count

503517 bp

Guanine Count

323517 bp

Cytosine Count

318225 bp

Genome Length

1649365 bp

Protein-coding Genes

1478 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
diacylglycerol kinaseBB465_01275Not AvailableNegative1511041 - 151142714497.0
hypothetical proteinBB465_01280Not AvailableNegative1511420 - 151243338187.2
acetone carboxylase subunit gammaBB465_01290Not AvailableNegative1512848 - 151334819685.7
acetone carboxylase subunit alphaBB465_01295Not AvailableNegative1513372 - 151566986504.5
acetone carboxylase subunit betaBB465_01300Not AvailableNegative1515681 - 151782278505.2
hypothetical proteinBB465_01305Not AvailableNegative1518053 - 151905438576.2
tigr00366 family proteinBB465_01310Not AvailableNegative1519179 - 152054349070.4
succinyl-coa--3-ketoacid-coa transferaseBB465_01315Not AvailableNegative1520563 - 152118622234.3
succinyl-coa--3-ketoacid-coa transferaseBB465_01320Not AvailableNegative1521183 - 152188125352.8
acetyl-coa acetyltransferaseBB465_01325Not AvailableNegative1521892 - 152306741141.8

Displaying genes 1391 – 1400 of 1520 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total