Helicobacter pylori strain 2025

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 2025 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella, allowing for mobility in its host-associated habitat. This strain exhibits a single cell arrangement and is classified as mesophilic, with an optimal growth temperature of 37°C. Notably, it has a unique biotic relationship, being free-living, yet it primarily resides in various hosts, including Homo sapiens, Gallus gallus, Aves, primates, mammals, amoeba, rodentia, and Cricetinae. The health effects associated with H. pylori strain 2025 are significant, as it is linked to numerous gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Additionally, the strain is implicated in conditions like gastroesophageal reflux disease (GERD) and functional dyspepsia, highlighting its role in the broader landscape of gastrointestinal health. In light of its pathogenicity in humans, H. pylori strain 2025 exemplifies a crucial microbial influence on human health, particularly concerning chronic gastrointestinal diseases and cancer development. The strain's capacity to thrive in diverse hosts raises important questions about its ecological adaptability and potential impact on host health, underscoring the intricate relationship between microbial inhabitants and their hosts in the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 2025

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 2025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2025 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

503780 bp

Thymine Count

504276 bp

Guanine Count

319139 bp

Cytosine Count

322964 bp

Genome Length

1650159 bp

Protein-coding Genes

1482 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
comb7 lipoproteinBB467_01070Not AvailablePositive217447 - 2175604291.5
competence protein combBB467_01075Not AvailablePositive217557 - 21830028737.6
conjugal transfer proteinBB467_01080Not AvailablePositive218300 - 21927437460.2
hypothetical proteinBB467_01085Not AvailablePositive219267 - 22039742021.0
mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomeraseBB467_01090Not AvailablePositive220463 - 22187553280.9
gdp-mannose 4,6-dehydrataseBB467_01095Not AvailablePositive221916 - 22306143833.4
gdp-fucose synthetaseBB467_01100Not AvailablePositive223054 - 22398634858.5
hypothetical proteinBB467_01105Not AvailableNegative224368 - 22466411298.4
hydrogenase expression/formation protein hypeBB467_01110Not AvailableNegative224840 - 22583836410.6
carbamoyltransferase hypfBB467_01115Not AvailableNegative225850 - 22810284952.8

Displaying genes 211 – 220 of 1524 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total