Helicobacter pylori strain 2025

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 2025 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella, allowing for mobility in its host-associated habitat. This strain exhibits a single cell arrangement and is classified as mesophilic, with an optimal growth temperature of 37°C. Notably, it has a unique biotic relationship, being free-living, yet it primarily resides in various hosts, including Homo sapiens, Gallus gallus, Aves, primates, mammals, amoeba, rodentia, and Cricetinae. The health effects associated with H. pylori strain 2025 are significant, as it is linked to numerous gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Additionally, the strain is implicated in conditions like gastroesophageal reflux disease (GERD) and functional dyspepsia, highlighting its role in the broader landscape of gastrointestinal health. In light of its pathogenicity in humans, H. pylori strain 2025 exemplifies a crucial microbial influence on human health, particularly concerning chronic gastrointestinal diseases and cancer development. The strain's capacity to thrive in diverse hosts raises important questions about its ecological adaptability and potential impact on host health, underscoring the intricate relationship between microbial inhabitants and their hosts in the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 2025

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 2025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2025 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

503780 bp

Thymine Count

504276 bp

Guanine Count

319139 bp

Cytosine Count

322964 bp

Genome Length

1650159 bp

Protein-coding Genes

1482 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB467_00860Not AvailableNegative179090 - 1793118209.56
n utilization substance protein bBB467_00865Not AvailableNegative179688 - 18010415520.0
6,7-dimethyl-8-ribityllumazine synthaseBB467_00870Not AvailableNegative180106 - 18057616986.7
3-deoxy-8-phosphooctulonate synthaseBB467_00875Not AvailableNegative180586 - 18141630284.6
carbonic anhydraseBB467_00880Not AvailableNegative181403 - 18206825719.7
orotidine 5'-phosphate decarboxylaseBB467_00885Not AvailablePositive182191 - 18287425422.2
pantoate--beta-alanine ligaseBB467_00890Not AvailablePositive182875 - 18370531227.2
Trna-gluNot AvailableNot AvailablePositive183719 - 183794Not Available
Trna-aspNot AvailableNot AvailablePositive183858 - 183934Not Available
Trna-valNot AvailableNot AvailablePositive183985 - 184060Not Available

Displaying genes 171 – 180 of 1524 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total