Helicobacter pylori strain 2025

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 2025 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella, allowing for mobility in its host-associated habitat. This strain exhibits a single cell arrangement and is classified as mesophilic, with an optimal growth temperature of 37°C. Notably, it has a unique biotic relationship, being free-living, yet it primarily resides in various hosts, including Homo sapiens, Gallus gallus, Aves, primates, mammals, amoeba, rodentia, and Cricetinae. The health effects associated with H. pylori strain 2025 are significant, as it is linked to numerous gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Additionally, the strain is implicated in conditions like gastroesophageal reflux disease (GERD) and functional dyspepsia, highlighting its role in the broader landscape of gastrointestinal health. In light of its pathogenicity in humans, H. pylori strain 2025 exemplifies a crucial microbial influence on human health, particularly concerning chronic gastrointestinal diseases and cancer development. The strain's capacity to thrive in diverse hosts raises important questions about its ecological adaptability and potential impact on host health, underscoring the intricate relationship between microbial inhabitants and their hosts in the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 2025

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 2025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2025 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

503780 bp

Thymine Count

504276 bp

Guanine Count

319139 bp

Cytosine Count

322964 bp

Genome Length

1650159 bp

Protein-coding Genes

1482 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-alanine--d-alanine ligase aBB467_02785Not AvailablePositive1340447 - 134149039696.0
2-hydroxy-6-oxohepta-2,4-dienoate hydrolaseBB467_02790Not AvailablePositive1341490 - 134221527544.5
udp-murnac-pentapeptide presynthetase murfBB467_02795Not AvailablePositive1342202 - 134368355826.8
hit family hydrolaseBB467_02800Not AvailablePositive1343693 - 134417818333.3
ribose-phosphate pyrophosphokinaseBB467_02805Not AvailablePositive1344270 - 134519933774.3
Trna-metNot AvailableNot AvailablePositive1345225 - 1345301Not Available
hypothetical proteinBB467_02820Not AvailableNegative1346431 - 134698519574.1
gtpaseBB467_02825Not AvailableNegative1347189 - 134764116758.3
rna pseudouridine synthaseBB467_02830Not AvailablePositive1347775 - 134875837675.4
hypothetical proteinBB467_02835Not AvailablePositive1348721 - 134996847588.4

Displaying genes 1211 – 1220 of 1524 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total