Helicobacter pylori strain 24013

Helicobacter pylori strain 24013 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella, which enables it to thrive in a host-associated habitat. This strain is notable for its optimal growth temperature of 37°C, placing it within the mesophilic temperature range. It has a single replicon and is surrounded by two membranes, indicating its complex cell structure. This bacterium has a wide range of hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), various Aves (birds), Primates, Mammalia, Amoeba, Rodentia, and Cricetinae (hamsters). Its biotic relationship is categorized as free-living, implying a potential for environmental persistence yet primarily relies on host interactions for survival. Helicobacter pylori strain 24013 is closely associated with significant health effects, particularly in humans. It is known to cause chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, including stomach carcinoma and mucosa-associated lymphoid tissue lymphoma. Furthermore, it contributes to gastrointestinal diseases such as GERD, gastritis, and peptic ulcer disease. The presence of this bacterium often results in an asymptomatic mucosal inflammatory response, which can progress to more severe conditions like atrophic gastritis and intestinal metaplasia. The pathogenicity of H. pylori strain 24013 highlights its role as a significant agent of gastrointestinal disease in humans, underscoring the importance of understanding its biology for public health interventions and treatment strategies. This strain exemplifies the complex interactions between a microbial pathogen and its host, influencing both individual health outcomes and broader ecological dynamics.