Helicobacter pylori strain 26024

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 26024 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella, allowing for mobility. This strain is adapted to a host-associated habitat and primarily infects Homo sapiens, but it has also been identified in various other hosts, including Gallus gallus, Aves, Primates, Mammalia, Amoeba, Rodentia, and Cricetinae. It thrives optimally at 37°C, within the mesophilic temperature range. Strain 26024 has a unique biotic relationship as it is free-living, despite its association with various hosts. It possesses a single replicon and is surrounded by two membranes, typical of Gram-negative bacteria. The health effects associated with H. pylori strain 26024 are significant and include chronic gastric inflammation, gastric cancer, gastric ulcers, and other gastrointestinal diseases. It is linked to various conditions such as gastritis, peptic ulcer disease, and mucosa-associated lymphoid tissue lymphoma, making it a major pathogenic agent in humans. The ecological insight provided by the distribution of H. pylori strain 26024 across multiple host species suggests a complex interplay between this bacterium and its environments, highlighting its adaptability and potential impact on both human health and the health of other animal species. This versatility may contribute to the ongoing research into its pathogenic mechanisms and the development of targeted therapies for the diseases it causes.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 26024

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 26024
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 26024 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

507039 bp

Thymine Count

513813 bp

Guanine Count

321847 bp

Cytosine Count

328305 bp

Genome Length

1671004 bp

Protein-coding Genes

1485 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductaseBB388_01285Not AvailableNegative246497 - 24753139093.6
sodium/glutamate symporterBB388_01290Not AvailableNegative247528 - 24875443934.1
saccharopine dehydrogenaseBB388_01295Not AvailablePositive248839 - 25003845115.4
cytochrome c oxidase accessory protein ccogBB388_01300Not AvailableNegative250048 - 25142452609.0
glycerol-3-phosphate acyltransferaseBB388_01305Not AvailablePositive251530 - 25219223821.3
dihydroneopterin aldolaseBB388_01310Not AvailablePositive252189 - 25254213828.9
iron-regulated proteinBB388_01315Not AvailablePositive252526 - 25285212500.1
tonb-dependent receptorBB388_01320Not AvailablePositive253021 - 25561295904.4
l-seryl-trna(sec) selenium transferaseBB388_01325Not AvailablePositive255838 - 25699843710.2
transcription termination factor nusaBB388_01330Not AvailablePositive257094 - 25828144674.4

Displaying genes 251 – 260 of 1530 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total