Helicobacter pylori strain 26084

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 26084 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella, which allows for its motility despite being described as non-mobile in certain contexts. This strain is notable for its habitat, primarily associating with various hosts including humans (Homo sapiens), birds (Gallus gallus, Aves), primates, mammals (Mammalia), rodents (Rodentia, Cricetinae), amoebas, and snails (Thais). Strain 26084 thrives optimally at 37°C and fits within the mesophilic temperature range. It possesses a single replicon and is enveloped by two membranes, which is a characteristic feature of Gram-negative organisms. The bacterium is known to have significant health implications, being associated with various gastrointestinal diseases, including chronic gastric inflammation, gastric ulcers, and several forms of gastric cancer, such as gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The pathogenicity of H. pylori strain 26084 predominantly affects humans, leading to conditions like gastritis, peptic ulcer disease, and functional dyspepsia. Its presence is linked to an asymptomatic mucosal inflammatory response, chronic gastritis, and other serious health issues such as dysplasia and atrophic gastritis. Ecologically, H. pylori strain 26084 exemplifies a complex biotic relationship within its human host, contributing to chronic inflammation and disease, highlighting its role in the human microbiome and the potential for its influence on gastric health and disease progression.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 26084

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 26084
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 26084 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

499943 bp

Thymine Count

508025 bp

Guanine Count

317779 bp

Cytosine Count

325440 bp

Genome Length

1651187 bp

Protein-coding Genes

1460 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
histidine kinaseBB386_00285Not AvailablePositive53695 - 5430623933.5
udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2, 6-diaminopimelate ligaseBB386_00290Not AvailablePositive54310 - 5565350730.1
transaldolaseBB386_00295Not AvailablePositive55656 - 5660635338.8
50s ribosomal protein l25/general stress protein ctcBB386_00300Not AvailablePositive56661 - 5719719898.7
aminoacyl-trna hydrolaseBB386_00305Not AvailablePositive57207 - 5776720911.3
permeaseBB386_00310Not AvailablePositive57777 - 5884441224.1
restriction endonucleaseBB386_00315Not AvailablePositive58965 - 5980731784.5
hypothetical proteinBB386_00320Not AvailableNegative60187 - 6131741353.0
copper resistance protein copdBB386_00325Not AvailablePositive61532 - 6196916248.0
carbonate dehydrataseBB386_00330Not AvailableNegative61966 - 6431786498.4

Displaying genes 61 – 70 of 1503 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total