Helicobacter pylori strain 26084

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 26084 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and presence of flagella, which allows for its motility despite being described as non-mobile in certain contexts. This strain is notable for its habitat, primarily associating with various hosts including humans (Homo sapiens), birds (Gallus gallus, Aves), primates, mammals (Mammalia), rodents (Rodentia, Cricetinae), amoebas, and snails (Thais). Strain 26084 thrives optimally at 37°C and fits within the mesophilic temperature range. It possesses a single replicon and is enveloped by two membranes, which is a characteristic feature of Gram-negative organisms. The bacterium is known to have significant health implications, being associated with various gastrointestinal diseases, including chronic gastric inflammation, gastric ulcers, and several forms of gastric cancer, such as gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The pathogenicity of H. pylori strain 26084 predominantly affects humans, leading to conditions like gastritis, peptic ulcer disease, and functional dyspepsia. Its presence is linked to an asymptomatic mucosal inflammatory response, chronic gastritis, and other serious health issues such as dysplasia and atrophic gastritis. Ecologically, H. pylori strain 26084 exemplifies a complex biotic relationship within its human host, contributing to chronic inflammation and disease, highlighting its role in the human microbiome and the potential for its influence on gastric health and disease progression.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 26084

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 26084
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 26084 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

499943 bp

Thymine Count

508025 bp

Guanine Count

317779 bp

Cytosine Count

325440 bp

Genome Length

1651187 bp

Protein-coding Genes

1460 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
molecular chaperone dnajBB386_04740Not AvailablePositive1508130 - 150889129834.5
nicotinate (nicotinamide) nucleotide adenylyltransferaseBB386_04745Not AvailableNegative1508888 - 150940319413.9
nickel responsive regulatorBB386_04750Not AvailableNegative1509396 - 150984217060.2
tonb-system energizer exbbBB386_04755Not AvailablePositive1510167 - 151060415819.9
tonb system transport protein exbdBB386_04760Not AvailablePositive1510601 - 151099014334.3
energy transducer tonbBB386_04765Not AvailablePositive1510956 - 151181031410.7
siderophore-mediated iron transporterBB386_04775Not AvailablePositive1512216 - 151288125617.8
dihydroorotaseBB386_04780Not AvailablePositive1512886 - 151390538019.2
hypothetical proteinBB386_04785Not AvailablePositive1513881 - 151499942892.3
hypothetical proteinBB386_04790Not AvailablePositive1515006 - 151556020903.5

Displaying genes 1371 – 1380 of 1503 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total