Helicobacter pylori strain 3136

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3136 is a microaerophilic, Gram-negative bacterium belonging to the spirilla shape category. This organism is primarily host-associated, with a habitat that includes several hosts such as Homo sapiens (humans), Gallus gallus (chickens), various Aves (birds), primates, and several mammalian and rodent species. It possesses a single replicon and is characterized by a biotic relationship that is free-living. Strain 3136 features a unique cellular arrangement of singles and is non-motile, despite the presence of flagella. It thrives optimally at 37°C within a mesophilic temperature range. The bacterium has a double membrane structure, a common trait among Gram-negative organisms. Helicobacter pylori strain 3136 is notable for its significant health effects on humans, being implicated in various gastrointestinal diseases. These include chronic gastric inflammation, peptic ulcer disease, gastric ulcers, and multiple forms of gastric cancer, including adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The strain can also lead to conditions such as chronic gastritis, GERD, and dyspepsia, reflecting its pathogenicity in human hosts. The presence of Helicobacter pylori in the gastrointestinal tract highlights its ecological role in host health, where it can induce both symptomatic and asymptomatic responses. Its association with serious health conditions underscores the importance of understanding its biology and ecology for effective management and treatment of related diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 3136

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 3136
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3136 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

490361 bp

Thymine Count

489651 bp

Guanine Count

317423 bp

Cytosine Count

308503 bp

Genome Length

1605938 bp

Protein-coding Genes

1424 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
endonucleaseBB445_00185Not AvailablePositive34433 - 3512826985.0
dna methyltransferaseBB445_00190Not AvailablePositive35125 - 3588329204.8
atp-dependent chaperone clpbBB445_00195Not AvailablePositive35956 - 3852696597.2
cytochrome c biogenesis proteinBB445_00200Not AvailablePositive38583 - 3930226449.8
dihydroorotaseBB445_00205Not AvailablePositive39312 - 4044542170.8
chlorohydrolaseBB445_00210Not AvailablePositive40433 - 4165945516.7
hypothetical proteinBB445_00215Not AvailablePositive41718 - 419609475.32
trna (n6-isopentenyl adenosine(37)-c2)-methylthiotransferase miabBB445_00220Not AvailablePositive42003 - 4328348178.3
hypothetical proteinBB445_00225Not AvailablePositive43323 - 4397624435.1
hypothetical proteinBB445_00230Not AvailablePositive43969 - 4494938506.2

Displaying genes 41 – 50 of 1466 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total