Helicobacter pylori strain 3136

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3136 is a microaerophilic, Gram-negative bacterium belonging to the spirilla shape category. This organism is primarily host-associated, with a habitat that includes several hosts such as Homo sapiens (humans), Gallus gallus (chickens), various Aves (birds), primates, and several mammalian and rodent species. It possesses a single replicon and is characterized by a biotic relationship that is free-living. Strain 3136 features a unique cellular arrangement of singles and is non-motile, despite the presence of flagella. It thrives optimally at 37°C within a mesophilic temperature range. The bacterium has a double membrane structure, a common trait among Gram-negative organisms. Helicobacter pylori strain 3136 is notable for its significant health effects on humans, being implicated in various gastrointestinal diseases. These include chronic gastric inflammation, peptic ulcer disease, gastric ulcers, and multiple forms of gastric cancer, including adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The strain can also lead to conditions such as chronic gastritis, GERD, and dyspepsia, reflecting its pathogenicity in human hosts. The presence of Helicobacter pylori in the gastrointestinal tract highlights its ecological role in host health, where it can induce both symptomatic and asymptomatic responses. Its association with serious health conditions underscores the importance of understanding its biology and ecology for effective management and treatment of related diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 3136

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 3136
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3136 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

490361 bp

Thymine Count

489651 bp

Guanine Count

317423 bp

Cytosine Count

308503 bp

Genome Length

1605938 bp

Protein-coding Genes

1424 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l17BB445_03615Not AvailableNegative1184949 - 118529913365.2
dna-directed rna polymerase subunit alphaBB445_03620Not AvailableNegative1185299 - 118633338510.4
30s ribosomal protein s4BB445_03625Not AvailableNegative1186345 - 118697123976.1
30s ribosomal protein s11BB445_03630Not AvailableNegative1186981 - 118737614014.2
30s ribosomal protein s13BB445_03635Not AvailableNegative1187399 - 118776113602.7
50s ribosomal protein l36BB445_03640Not AvailableNegative1187765 - 11878784321.68
translation initiation factor if-1BB445_03645Not AvailableNegative1187956 - 11881748348.36
type i methionyl aminopeptidaseBB445_03650Not AvailableNegative1188174 - 118893527490.6
preprotein translocase subunit secyBB445_03655Not AvailableNegative1188935 - 119019745831.7
50s ribosomal protein l15BB445_03660Not AvailableNegative1190235 - 119063614661.9

Displaying genes 1081 – 1090 of 1466 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total