Helicobacter pylori strain 22317

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22317 is a Gram-negative bacterium characterized by its spirilla shape and microaerophilic oxygen requirement. It is distinguished by its single-cell arrangement and the presence of flagella, which contribute to its motility. This strain is mesophilic, with an optimal growth temperature of 37°C. H. pylori strain 22317 is associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Aves (birds), primates, and several mammalian and rodent species. Its biotic relationship is classified as free-living, indicating that it can survive independently within its host-associated habitats. The bacterium is known for its significant health effects, which include a wide range of gastrointestinal diseases. These effects encompass chronic gastric inflammation, gastric ulcers, and various forms of cancer, such as gastric carcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Specifically, it is implicated in conditions like peptic ulcer disease, chronic gastritis, and dyspepsia, reflecting its role in both symptomatic and asymptomatic mucosal inflammatory responses. Interestingly, H. pylori strain 22317 highlights the complex interplay between microbial pathogens and host health, illustrating how a single bacterial strain can lead to diverse health outcomes in different host species. The strain's pathogenicity in humans underscores its relevance in clinical microbiology and public health, as it poses a risk for serious gastrointestinal diseases. Understanding its characteristics and effects can enhance our knowledge of its role in human health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 22317

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 22317
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22317 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

505635 bp

Thymine Count

507013 bp

Guanine Count

323054 bp

Cytosine Count

322418 bp

Genome Length

1658120 bp

Protein-coding Genes

1470 genes

Non-Coding Genes

44 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptide abc transporter atp-binding proteinBB423_02895Not AvailableNegative1192497 - 119336032270.6
diguanylate cyclaseBB423_02900Not AvailableNegative1193372 - 119422930851.0
peptide abc transporter permeaseBB423_02905Not AvailableNegative1194229 - 119523336846.2
peptide abc transporter substrate-binding proteinBB423_02910Not AvailableNegative1195244 - 119689362401.9
50s ribosomal protein l27BB423_02915Not AvailableNegative1197010 - 11972769778.76
50s ribosomal protein l21BB423_02920Not AvailableNegative1197291 - 119760511817.7
flagellar biosynthesis protein flglBB423_02925Not AvailablePositive1197847 - 120033391948.8
acylamide amidohydrolaseBB423_02930Not AvailableNegative1200415 - 120143437763.0
bifunctional aminodeoxychorismate synthase component i/aminotransferaseBB423_02935Not AvailableNegative1201629 - 120330864710.8
hypothetical proteinBB423_02940Not AvailableNegative1203309 - 120418133823.3

Displaying genes 1111 – 1120 of 1514 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total