Eikenella corrodens strain NML04-0072

Gram-negativeRodFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Eikenella

Description

Eikenella corrodens strain NML04-0072 is a Gram-negative, facultative anaerobic rod that is part of the normal flora in various human habitats, including the gastrointestinal tract, genital tracts, oral cavity, oropharynx, respiratory tract, and urogenital tract. This strain is specifically associated with Homo sapiens, highlighting its role as a commensal organism that can also act as an opportunistic pathogen. Clinically, Eikenella corrodens is known to be implicated in several health conditions. It has been associated with serious infections such as endocarditis, liver abscesses, and lung abscesses. Additionally, it can cause epidural abscesses, vulvar abscesses, periodontitis-like diseases, and other types of visceral abscesses. The range of infections caused by this organism indicates its potential to cause significant health complications, especially in immunocompromised individuals. Given its presence in various human body sites and its association with opportunistic infections, Eikenella corrodens serves as an important reminder of the complexities of human microbiota. While it is typically a benign inhabitant, under certain conditions it can transition to a pathogenic role, contributing to a spectrum of diseases that emphasize the delicate balance of microbial communities in human health. Understanding the pathogenic potential of strains like NML04-0072 is vital for developing effective treatment and prevention strategies for the infections they cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusEikenella
SpeciesEikenella corrodens
Strainstrain NML04-0072

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Eikenella corrodens strain NML04-0072
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgastrointestinal; genital tracts; intestinal; oral cavity; oropharyngeal; oropharynx; respiratory; upper respiratory tract; urogenital tract
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Eikenella corrodens strain NML04-0072 Eikcor_contig000050, whole

Gene Summary

Adenine Count

539825 bp

Thymine Count

538824 bp

Guanine Count

671897 bp

Cytosine Count

672493 bp

Genome Length

2423039 bp

Protein-coding Genes

2190 genes

Non-Coding Genes

199 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transposaseA7P90_11935Not AvailableNegative2392960 - 239332514405.7
hypothetical proteinA7P90_11940Not AvailablePositive2393573 - 239391411685.0
sulfurtransferaseA7P90_11945Not AvailablePositive2393991 - 239437714060.7
nicotinate (nicotinamide) nucleotide adenylyltransferaseA7P90_11950Not AvailableNegative2394489 - 239510322696.2
holliday junction dna helicase ruvaA7P90_11955Not AvailableNegative2395268 - 239584920409.7
nema proteinA7P90_11960Not AvailablePositive2395952 - 239642517114.5
glutamine--fructose-6-phosphate aminotransferaseA7P90_11965Not AvailablePositive2396540 - 239838166656.8
heme biosynthesis protein hemyA7P90_11970Not AvailableNegative2398630 - 239985045521.4
heme biosynthesis operon protein hemxA7P90_11975Not AvailableNegative2399847 - 240110044016.3
uroporphyrinogen-iii synthaseA7P90_11980Not AvailableNegative2401183 - 240193826941.5

Displaying genes 2361 – 2370 of 2389 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Epidural abscessCausesPMC12375837
Abscess lesionsCausesPMC12375837
Vulvar abscessCausesPMC1791056
Periodontitis-like diseaseCausesPMC422167
Visceral abscessesCausesPMC5767030
Liver abscessesCausesPMC5767030
EndocarditisCausesPMC5767030
Liver abscessCausesPMC5767030
Lung abscessCausesPMC7236361
Infective endocarditisCausesPMC7236361

Displaying health effects 1 – 10 of 11 in total