Fusobacterium necrophorum subsp. funduliforme strain LS_1264

anaerobic

Kingdom

Fusobacteriati

Phylum

Fusobacteriota

Class

Fusobacteriia

Order

Fusobacteriales

Family

Fusobacteriaceae

Genus

Fusobacterium

Description

Fusobacterium necrophorum subsp. funduliforme strain LS_1264 is a Gram-negative, anaerobic bacterium known for its pathogenic potential in humans and animals. This strain is characterized by the presence of flagella, which may contribute to its mobility in anaerobic environments. It has a single replicon, indicating a streamlined genomic structure. This subspecies is notably associated with several health issues, particularly in Homo sapiens and Bos species. In humans, F. necrophorum subsp. funduliforme has been linked to serious conditions such as liver abscesses and Lemierre's syndrome, a condition that can lead to septic thrombophlebitis and systemic infection. In bovines, the bacterium may also play a role in similar pathologies, affecting livestock health and productivity. The strain is cataloged under the accession number LVEA00000000.1, which aids in its identification and study within microbiological research. The anaerobic nature of this bacterium suggests that it thrives in environments devoid of oxygen, which is typical for various deep tissues or abscesses where it may cause infection. Ecologically, Fusobacterium necrophorum subsp. funduliforme strain LS_1264 reflects the complex interactions between microbial species and their hosts. Its pathogenicity highlights the importance of understanding anaerobic bacterial communities in both human and veterinary medicine, as these interactions can have significant health implications.

Taxonomy

KingdomFusobacteriati
PhylumFusobacteriota
ClassFusobacteriia
OrderFusobacteriales
FamilyFusobacteriaceae
GenusFusobacterium
SpeciesFusobacterium necrophorum
Strainsubsp. funduliforme strain LS_1264

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Fusobacterium necrophorum subsp. funduliforme strain LS_1264

Gene Summary

Adenine Count

757009 bp

Thymine Count

774800 bp

Guanine Count

392707 bp

Cytosine Count

409987 bp

Genome Length

2334503 bp

Protein-coding Genes

2131 genes

Non-Coding Genes

74 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-glnNot AvailableNot AvailablePositive805438 - 805512Not Available
septation protein spovgA2J07_09020Not AvailableNegative805602 - 80588910849.2
4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol kinaseA2J07_09025Not AvailableNegative805912 - 80677533371.1
heat-shock protein hsp15A2J07_09030Not AvailableNegative806762 - 80706711827.5
transcription-repair coupling factorA2J07_09035Not AvailableNegative807136 - 810087117101.0
trna uridine(34) 5-carboxymethylaminomethyl synthesis enzyme mnmgA2J07_09040Not AvailableNegative810142 - 81198969401.2
trna modification gtpaseA2J07_09045Not AvailableNegative811999 - 81337251057.2
jag proteinA2J07_09050Not AvailableNegative813386 - 81408127313.7
hypothetical proteinA2J07_09055Not AvailableNegative814084 - 81470123465.8
membrane protein insertion efficiency factor yiddA2J07_09060Not AvailableNegative814719 - 8149288058.97

Displaying genes 761 – 770 of 2205 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

216 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000305tetrathionateO6S4Chemical structure of tetrathionateNot available
Average224.24Da
Monoisotopic223.8588696Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da

Displaying 1–10 of 216 metabolites

Health Effects

Health ConditionRelationReference
Liver abscessCausesPMC10195197
Lemierre s syndromeCausesPMC9009667
Lemierre's syndromeCausesPMC11116006
Lemierre's syndromeCausesPMC11415938
Lemierre's syndromeCausesPMC8503589
PharyngitisCausesPMC8503589

Displaying health effects 1 – 6 of 6 in total