Streptococcus pneumoniae strain NTPn 239

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae strain NTPn 239 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. It is a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 30°C, placing it within the mesophilic range. This strain is non-motile and lacks flagella, which may influence its mode of transmission and colonization. NTPn 239 is known to be free-living and has been identified in various hosts, including humans (Homo sapiens), chickens (Gallus gallus), guinea pigs (Cavia), and other small mammals such as Meriones unguiculatus and Chinchilla. Its pathogenicity primarily affects humans, leading to a range of serious health conditions, including bacteremia, pneumonia, meningitis, otitis media, and other respiratory infections. The strain is associated with both community-acquired pneumonia and invasive pneumococcal disease (IPD), which emphasizes its role in significant public health challenges. The presence of multiple habitats and its relationship with diverse hosts suggest that S. pneumoniae strain NTPn 239 may play a crucial role in the ecology of respiratory pathogens. Its ability to cause a spectrum of infections, particularly in vulnerable populations, highlights the importance of understanding its transmission dynamics and potential reservoirs in both human and animal populations. This awareness is essential for developing effective prevention and treatment strategies against the diseases caused by this pathogen.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
Strainstrain NTPn 239

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae strain NTPn 239
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Cavia
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pneumoniae strain NTPn 239 NTPn_239_contig_99, whole

Gene Summary

Adenine Count

639606 bp

Thymine Count

637751 bp

Guanine Count

427262 bp

Cytosine Count

417281 bp

Genome Length

2122800 bp

Protein-coding Genes

1907 genes

Non-Coding Genes

105 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
integraseAZJ17_07665Not AvailableNegative1685198 - 168553913444.9
transposaseAZJ17_07670Not AvailableNegative1685539 - 16856735399.58
phosphoglycerate mutaseAZJ17_07675Not AvailableNegative1686301 - 168692123335.9
aminoacyl-trna deacylaseAZJ17_07680Not AvailableNegative1686921 - 168740317622.8
hypothetical proteinAZJ17_07685Not AvailableNegative1687403 - 168824530548.3
glycosyl hydrolase family 25AZJ17_07690Not AvailableNegative1688340 - 168914030081.8
bifunctional n-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferaseAZJ17_07695Not AvailablePositive1689284 - 169066349390.6
adp-ribose pyrophosphataseAZJ17_07700Not AvailablePositive1690673 - 169121820515.5
foldaseAZJ17_07705Not AvailablePositive1691230 - 169154411769.5
5'-methylthioadenosine nucleosidaseAZJ17_07710Not AvailablePositive1691561 - 169225324657.4

Displaying genes 1631 – 1640 of 2012 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community acquired pneumoniaCausesPMC10663590
Bacterial pneumoniaCausesPMC10663590
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026
SinusitisCausesPMC12375837
MeningitisCausesPMC12680174
PneumoniaCausesPMC12680174
Otitis mediaCausesPMC3695778
Purulent pericarditisCausesPMC3853837
InfectionsCausesPMC4120200

Displaying health effects 1 – 10 of 79 in total