Streptococcus pneumoniae strain NTPn 239

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae strain NTPn 239 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. It is a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 30°C, placing it within the mesophilic range. This strain is non-motile and lacks flagella, which may influence its mode of transmission and colonization. NTPn 239 is known to be free-living and has been identified in various hosts, including humans (Homo sapiens), chickens (Gallus gallus), guinea pigs (Cavia), and other small mammals such as Meriones unguiculatus and Chinchilla. Its pathogenicity primarily affects humans, leading to a range of serious health conditions, including bacteremia, pneumonia, meningitis, otitis media, and other respiratory infections. The strain is associated with both community-acquired pneumonia and invasive pneumococcal disease (IPD), which emphasizes its role in significant public health challenges. The presence of multiple habitats and its relationship with diverse hosts suggest that S. pneumoniae strain NTPn 239 may play a crucial role in the ecology of respiratory pathogens. Its ability to cause a spectrum of infections, particularly in vulnerable populations, highlights the importance of understanding its transmission dynamics and potential reservoirs in both human and animal populations. This awareness is essential for developing effective prevention and treatment strategies against the diseases caused by this pathogen.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
Strainstrain NTPn 239

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae strain NTPn 239
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Cavia
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pneumoniae strain NTPn 239 NTPn_239_contig_99, whole

Gene Summary

Adenine Count

639606 bp

Thymine Count

637751 bp

Guanine Count

427262 bp

Cytosine Count

417281 bp

Genome Length

2122800 bp

Protein-coding Genes

1907 genes

Non-Coding Genes

105 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
elongation factor pAZJ17_00955Not AvailablePositive1413919 - 141447920601.6
hypothetical proteinAZJ17_00960Not AvailablePositive1414501 - 141489014152.2
antitermination protein nusbAZJ17_00965Not AvailablePositive1414883 - 141530515961.1
abortive phage infection proteinAZJ17_00970Not AvailableNegative1415603 - 141588110955.2
acetyl-coa carboxylaseAZJ17_00975Not AvailableNegative1416096 - 14162817088.17
acetyl-coa carboxylase carboxyl transferase subunit alphaAZJ17_00980Not AvailableNegative1416440 - 141720728235.2
acetyl-coa carboxylase carboxyl transferase subunit betaAZJ17_00985Not AvailableNegative1417204 - 141807031787.8
acetyl-coa carboxylase biotin carboxylase subunitAZJ17_00990Not AvailableNegative1418107 - 141947449542.4
3-hydroxyacyl-[acyl-carrier-protein] dehydratase fabzAZJ17_00995Not AvailableNegative1419486 - 141990815315.0
acetyl-coa carboxylase biotin carboxyl carrier protein subunitAZJ17_01000Not AvailableNegative1419905 - 142039017034.4

Displaying genes 1401 – 1410 of 2012 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community acquired pneumoniaCausesPMC10663590
Bacterial pneumoniaCausesPMC10663590
MeningitisCausesPMC11116026
EncephalitisCausesPMC11116026
SinusitisCausesPMC12375837
MeningitisCausesPMC12680174
PneumoniaCausesPMC12680174
Otitis mediaCausesPMC3695778
Purulent pericarditisCausesPMC3853837
InfectionsCausesPMC4120200

Displaying health effects 1 – 10 of 79 in total